| # | Date | Film | Gross (USD) | Openings in the top ten |
| 1 | January 5, 2020 | Jumanji: The Next Level | $1,688,078 | Charlie's Angels (#2), Richard Jewell (#7), La Marca del Demonio (#9), The Lighthouse (#10) |
| 2 | January 12, 2020 | $1,055,102 | Underwater (#2), Perdida (#3), 10 Minutes Gone (#9), La liga de los 5 (#10) |
| 3 | January 19, 2020 | Bad Boys for Life | $3,824,093 | 1917 (#2), The Hollow Child (#8), Judy (#9) |
| 4 | January 26, 2020 | $2,395,092 | Cindy la Regia (#2), Little Women (#4), Jojo Rabbit (#5), The Turning (#8) |
| 5 | February 2, 2020 | Dolittle | $3,495,029 | Gretel & Hansel (#4), Countdown (#7), Bombshell (#8), Like a Boss (#10) |
| 6 | February 9, 2020 | Birds of Prey | $4,184,092 | |
| 7 | February 16, 2020 | Sonic the Hedgehog | $6,894,019 | Loco por Ti (#3), The Grudge (#4), The Gentlemen (#8) |
| 8 | February 23, 2020 | $3,545,092 | The Call of the Wild (#2), Just Mercy (#6) |
| 9 | March 1, 2020 | $2,273,409 | The Invisible Man (#2), Rebelión de los Godínez (#4), An Officer and a Spy (#10) |
| 10 | March 8, 2020 | Onward | $2,854,091 | Malasaña 32 (#5) |
| 11 | March 15, 2020 | $1,169,028 | Bloodshot (#2), Veinteañera, Divorciada y Fantástica (#3), My Spy (#6) |
| 12 | March 22, 2020 | Veinteañera, Divorciada y Fantástica | $169,098 | Night Hunter (#4), A Score to Settle (#5) |
| 13 | March 29, 2020 | Theaters closed due to the COVID-19 pandemic. |
| 14 | April 5, 2020 |
| 15 | April 12, 2020 |
| 16 | April 19, 2020 |
| 17 | April 26, 2020 |
| 18 | May 3, 2020 |
| 19 | May 10, 2020 |
| 20 | May 17, 2020 |
| 21 | May 24, 2020 |
| 22 | May 31, 2020 |
| 23 | June 7, 2020 |
| 24 | June 14, 2020 |
| 25 | June 21, 2020 |
| 26 | June 28, 2020 |
| 27 | July 5, 2020 | The Invisible Man | $1,097 | |
| 28 | July 12, 2020 | Dolittle | $1,079 | |
| 29 | July 19, 2020 | The Addams Family | $954 | |
| 30 | July 26, 2020 | The Invisible Man | $209 | |
| 31 | August 2, 2020 | The Hunt | $27,981 | |
| 32 | August 9, 2020 | $33,027 | |
| 33 | August 16, 2020 | $45,146 | I Still Believe (#2) |
| 34 | August 23, 2020 | Scoob! | $250,932 | Cuidado con lo que Deseas (#2), Jurassic World: Fallen Kingdom (#3) |
| 35 | August 30, 2020 | $257,332 | Fantasy Island (#2), The Secret: Dare to Dream (#4), Inception (#6), Guns Akimbo (#9) |
| 36 | September 6, 2020 | The New Mutants | $554,096 | The Climbers (#5), Ordinary Love (#9) |
| 37 | September 13, 2020 | $419,009 | Organizadora de Bodas (#4), Spycies (#6) |
| 38 | September 20, 2020 | Tenet | $596,244 | Donne Moi Des Alies (#7) |
| 39 | September 27, 2020 | Break the Silence: The Movie | $745,029 | Trolls: World Tour (#2), El Club de los Idealistas (#5), Sin Origen (#7) |
| 40 | October 4, 2020 | Trolls: World Tour | $285,093 | Sputnik (#4), Padre No Hay Más Que Uno (#7), Lassie Come Home (#8) |
| 41 | October 11, 2020 | Tenet | $209,091 | Red Shoes and the Seven Dwarfs (#4), Apparition (#5), Bill & Ted Face the Music (#7) |
| 42 | October 18, 2020 | Honest Thief | $535,948 | Cats & Dogs 3: Paws Unite! (#5), Girl on the Third Floor (#8) |
| 43 | October 25, 2020 | Nuevo Orden | $409,209 | The Empty Man (#4) |
| 44 | November 1, 2020 | The Witches | $835,029 | The Craft: Legacy (#4), The Collini Case (#10) |
| 45 | November 8, 2020 | $515,000 | Peninsula (#2) |
| 46 | November 15, 2020 | $372,000 | Freaky (#3), El Camino de Xico (#5), Weathering with You (#7), Dark Light (#8) |
| 47 | November 22, 2020 | Greenland | $739,019 | El Baile de los 41 (#3), 100% Wolf (#5), LM5: The Tour - The Film (#10) |
| 48 | November 29, 2020 | $539,091 | Z (#5), Henchmen (#9) |
| 49 | December 6, 2020 | $392,003 | Wonder Woman (#2), My Hero Academia: Heroes Rising (#3), Tunnelen (#4), Mario Puzo's The Godfather, Coda: The Death of Michael Corleone (#10) |
| 50 | December 13, 2020 | The Croods: A New Age | $945,920 | Happiest Season (#4) |
| 52 | December 20, 2020 | Wonder Woman 1984 | $1,674,091 | |
| 53 | December 27, 2020 | $688,004 | Dime Cuando Tú (#3) |
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