RABEPK

RABEPK
Identifiers
Aliases	RABEPK, RAB9P40, bA65N13.1, p40, Rab9 effector protein with kelch motifs
External IDs	OMIM: 605962 MGI: 2139530 HomoloGene: 48772 GeneCards: RABEPK
Gene location (Human)
Chr.	Chromosome 9 (human)
End	125,234,161 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	34,689,924 bp
RNA expression pattern
	Top expressed in
	right lobe of liver; ; nucleus accumbens; ; putamen; ; caudate nucleus; ; prefrontal cortex; ; stromal cell of endometrium; ; Brodmann area 9; ; cingulate gyrus; ; middle temporal gyrus; ; islet of Langerhans;
	Top expressed in
	spermatid; ; seminiferous tubule; ; spermatocyte; ; yolk sac; ; superior frontal gyrus; ; facial motor nucleus; ; medial vestibular nucleus; ; lateral geniculate nucleus; ; proximal tubule; ; interventricular septum;
	More reference expression data
	More reference expression data
Orthologs
	10244
	227746
	ENSG00000136933
	ENSMUSG00000070953
	Q7Z6M1; Q5T1S5
	Q8VCH5
	NM_001174152; NM_001174153; NM_005833
	NM_145522; NM_001374669
	NP_001167623; NP_001167624; NP_005824
	NP_663497; NP_001361598
	Wikidata
View/Edit Human	View/Edit Mouse

Rab9 effector protein with Kelch motifs also known as p40 is a protein that in humans is encoded by the RABEPK gene.^[5]^[6]

Membrane-associated p40, in together with RAB9A, facilitates the transport of the mannose 6-phosphate receptor (MPR) from endosomes to the trans-Golgi network.^[5]

Interactions[edit]

RABEPK has been shown to interact with RAB9A^[5] and FYVE finger-containing phosphoinositide kinase.^[7]

References[edit]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000136933 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000070953 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ ^a ^b ^c Diaz E, Schimmoller F, Pfeffer SR (Aug 1997). "A novel Rab9 effector required for endosome-to-TGN transport". J Cell Biol. 138 (2): 283–90. doi:10.1083/jcb.138.2.283. PMC 2138197. PMID 9230071.
^ "Entrez Gene: RABEPK Rab9 effector protein with kelch motifs".
^ Ikonomov, Ognian C; Sbrissa Diego; Mlak Krzysztof; Deeb Robert; Fligger Jason; Soans Aleric; Finley Russell L; Shisheva Assia (Dec 2003). "Active PIKfyve associates with and promotes the membrane attachment of the late endosome-to-trans-Golgi network transport factor Rab9 effector p40". J. Biol. Chem. 278 (51): 50863–71. doi:10.1074/jbc.M307260200. ISSN 0021-9258. PMID 14530284.

External links[edit]

RABEPK human gene location in the UCSC Genome Browser.
RABEPK human gene details in the UCSC Genome Browser.

This article on a gene on human chromosome 9 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000136933 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000070953 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9230071-5] Diaz E, Schimmoller F, Pfeffer SR (Aug 1997). "A novel Rab9 effector required for endosome-to-TGN transport". J Cell Biol. 138 (2): 283–90. doi:10.1083/jcb.138.2.283. PMC 2138197. PMID 9230071.

[entrez-6] "Entrez Gene: RABEPK Rab9 effector protein with kelch motifs".

[pmid14530284-7] Ikonomov, Ognian C; Sbrissa Diego; Mlak Krzysztof; Deeb Robert; Fligger Jason; Soans Aleric; Finley Russell L; Shisheva Assia (Dec 2003). "Active PIKfyve associates with and promotes the membrane attachment of the late endosome-to-trans-Golgi network transport factor Rab9 effector p40". J. Biol. Chem. 278 (51): 50863–71. doi:10.1074/jbc.M307260200. ISSN 0021-9258. PMID 14530284.

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RABEPK

Interactions[edit]

References[edit]

Further reading[edit]

External links[edit]

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