Granuloma gluteale infantum
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| Granuloma gluteale infantum | |
|---|---|
| Specialty | Dermatology |
Granuloma gluteale infantum is a cutaneous condition that appears in the anogenital region of infants as a complication of diaper dermatitis.[1] According to some, no granulomas are found.[2]
Signs and symptoms[edit]
In cases of primary irritant contact dermatitis, the lesions manifest clinically as numerous asymptomatic erythematous papules and nodules in the diaper area.[3]
Causes[edit]
Granuloma gluteale infantum is an uncommon dermatosis of infancy with an unknown etiology.[4] Contributing factors include prolonged use of fluorinated steroids,[5] and benzocaine,[6] diaper occlusion in incontinent adults and infants,[7] candidiasis,[8] and irritant contact dermatitis.[9]
Diagnosis[edit]
The histological picture shows an underlying hyperplastic epidermis and parakeratosis, accompanied by a non-specific perivascular dermal infiltrate made up of neutrophils, histiocytes, lymphocytes, plasma cells, and eosinophils.[10]
Treatment[edit]
In order to treat granuloma gluteale infantum, the diaper area needs to be kept dry and clean, and the irritant should be eliminated or lessened. It is recommended to use a barrier cream, such as zinc oxide.[11]
See also[edit]
References[edit]
- ^ Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. ISBN 978-1-4160-2999-1.
- ^ De Zeeuw R, Van Praag MC, Oranje AP (2000). "Granuloma gluteale infantum: a case report". Pediatr Dermatol. 17 (2): 141–3. doi:10.1046/j.1525-1470.2000.01734.x. hdl:1765/56610. PMID 10792807. S2CID 23487761.
- ^ Leung, Alexander K. C.; Leong, Kin Fon; Lam, Joseph M. (June 7, 2021). "Successful Treatment of Recalcitrant Granuloma Gluteale Infantum with Topical Tacrolimus 0.03% Ointment". Case Reports in Pediatrics. 2021. Hindawi Limited: 1–5. doi:10.1155/2021/9994067. ISSN 2090-6811. PMC 8203409. PMID 34194861.
- ^ Konya, Joseph; Gow, Elizabeth (1996). "Granuloma gluteale infantum". Australasian Journal of Dermatology. 37 (1). Wiley: 57–58. doi:10.1111/j.1440-0960.1996.tb00999.x. ISSN 0004-8380. S2CID 29839550.
- ^ Pons, S (1976). "[Granuloma gluteale infantum]". Medicina Cutanea Ibero-latino-americana. 4 (5): 359–364. PMID 1035390.
- ^ Dytoc, Marlene T.; Fiorillo, Loretta; Liao, Janice; Krol, Alfons L. (June 1, 2002). "Granuloma Gluteale Adultorum Associated with Use of Topical Benzocaine Preparations: Case Report and Literature Review". Journal of Cutaneous Medicine and Surgery: Incorporating Medical and Surgical Dermatology. 6 (3). SAGE Publications: 221–225. doi:10.1007/s10227-001-0042-9. ISSN 1203-4754. PMID 12001002.
- ^ Mostafa, Wedad Z.; Abahussein, Abdulaziz A.; Alzayer, Ahmed A. (1992). "Diaper Area Granuloma of Incontinence". The Journal of Dermatology. 19 (5). Wiley: 319–322. doi:10.1111/j.1346-8138.1992.tb03232.x. ISSN 0385-2407. PMID 1644958. S2CID 32495128.
- ^ De Zeeuw, Raymond; Van Praag, Marinus C. G.; Oranje, Arnold P. (2000). "Granuloma Gluteale Infantum: A Case Report". Pediatric Dermatology. 17 (2). Wiley: 141–143. doi:10.1046/j.1525-1470.2000.01734.x. hdl:1765/56610. ISSN 0736-8046. PMID 10792807. S2CID 23487761.
- ^ Walsh, S S; Robson, W J (June 1, 1988). "Granuloma gluteale infantum: an unusual complication of napkin dermatitis". Emergency Medicine Journal. 5 (2). BMJ: 113–115. doi:10.1136/emj.5.2.113. ISSN 1472-0205. PMC 1285498. PMID 3408529.
- ^ Al-Natour, SaharH; Al-Faraidy, NadyaA (2010). "A forgotten complication of diaper dermatitis: Granuloma gluteale infantum". Journal of Family and Community Medicine. 17 (2). Medknow: 107. doi:10.4103/1319-1683.71994. ISSN 2230-8229. PMC 3045094. PMID 21359035.
- ^ Ingersoll, Zachary; Garza-Chapa, Juana Irma; Pham, Ryan; Malouf, Peter; Susa, Joseph; Weis, Stephen (August 23, 2018). "Recurrent Granuloma Gluteale Infantum Secondary to Fecal Overflow Incontinence". Case Reports in Dermatology. 10 (2). S. Karger AG: 203–207. doi:10.1159/000492270. ISSN 1662-6567. PMC 6167654. PMID 30283312.
Further reading[edit]
- Sweidan, Nada A. (December 1, 1989). "Skin Nodules Over the Diaper Area". Archives of Dermatology. 125 (12). American Medical Association (AMA): 1705. doi:10.1001/archderm.1989.01670240105026. ISSN 0003-987X.
- Ramos Pinheiro, Rita; Matos-Pires, Eugénia; Baptista, Juliana; Lencastre, André (February 1, 2018). "Granuloma Glutaeale Infantum: A Re-emerging Complication of Diaper Dermatitis". Pediatrics. 141 (2). American Academy of Pediatrics (AAP). doi:10.1542/peds.2016-2064. hdl:10400.17/4425. ISSN 0031-4005. PMID 29298826.