List of EC numbers (EC 1)

This list contains a list of EC numbers for the first group, EC 1, oxidoreductases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology. All official information is tabulated at the website of the committee.^[1] The database is developed and maintained by Andrew McDonald.^[2]

EC 1.1 Acting on the CH-OH group of donors

EC 1.1.4 With a disulfide as acceptor

EC 1.1.4.1: Now EC 1.17.4.4, vitamin-K-epoxide reductase (warfarin-sensitive)
EC 1.1.4.2: Now EC 1.17.4.5, vitamin-K-epoxide reductase (warfarin-insensitive)

EC 1.1.5 With a quinone or similar compound as acceptor

EC 1.1.5.1: deleted, see EC 1.1.99.18 cellobiose dehydrogenase (acceptor)
EC 1.1.5.2: quinoprotein glucose dehydrogenase
EC 1.1.5.3: glycerol-3-phosphate dehydrogenase (quinone)
EC 1.1.5.4: malate dehydrogenase (quinone)
EC 1.1.5.5: alcohol dehydrogenase (quinone)
EC 1.1.5.6: formate dehydrogenase-N
EC 1.1.5.7: cyclic alcohol dehydrogenase (quinone)
EC 1.1.5.8: quinate dehydrogenase (quinone)

EC 1.1.9 With a copper protein as acceptor

EC 1.1.9.1: alcohol dehydrogenase (azurin)

EC 1.1.98 With other, known, acceptors

EC 1.1.98.1: Now EC 1.1.9.1, alcohol dehydrogenase (azurin)
EC 1.1.98.2: glucose-6-phosphate dehydrogenase (coenzyme-F₄₂₀)
EC 1.1.98.3: decaprenylphospho-β-D-ribofuranose 2-oxidase
EC 1.1.98.3: decaprenylphospho-β-D-ribofuranose 2-dehydrogenase
EC 1.1.98.4: F₄₂₀H₂:quinone oxidoreductase
EC 1.1.98.5: secondary-alcohol dehydrogenase (coenzyme-F₄₂₀)
EC 1.1.98.6: ribonucleoside-triphosphate reductase (formate)
EC 1.1.98.7: serine-type anaerobic sulfatase-maturating enzyme

EC 1.1.99 With unknown physiological acceptors

EC 1.1.99.1: choline dehydrogenase
EC 1.1.99.2: L-2-hydroxyglutarate dehydrogenase
EC 1.1.99.3: gluconate 2-dehydrogenase (acceptor)
EC 1.1.99.4: dehydrogluconate dehydrogenase
EC 1.1.99.5: now EC 1.1.5.3, glycerol-3-phosphate dehydrogenase
EC 1.1.99.6: D-2-hydroxy-acid dehydrogenase
EC 1.1.99.7: lactate—malate transhydrogenase
EC 1.1.99.8: Now EC 1.1.2.7, methanol dehydrogenase (cytochrome c) and EC 1.1.2.8, alcohol dehydrogenase (cytochrome c).
EC 1.1.99.9: pyridoxine 5-dehydrogenase
EC 1.1.99.10: Now EC 1.1.5.9, glucose 1-dehydrogenase (FAD, quinone)
EC 1.1.99.11: Now classified as EC 1.1.5.14, fructose 5-dehydrogenase
EC 1.1.99.12: sorbose dehydrogenase
EC 1.1.99.13: glucoside 3-dehydrogenase
EC 1.1.99.14: glycolate dehydrogenase
EC 1.1.99.15: Now EC 1.5.1.20, methylenetetrahydrofolate reductase [NAD(P)H]
EC 1.1.99.16: Now EC EC 1.1.5.4, malate dehydrogenase (quinone)
EC 1.1.99.17: Now EC 1.1.5.2, quinoprotein glucose dehydrogenase
EC 1.1.99.18: cellobiose dehydrogenase (acceptor)
EC 1.1.99.19: Now EC 1.17.99.4, uracil/thymine dehydrogenase
EC 1.1.99.20: alkan-1-ol dehydrogenase (acceptor)
EC 1.1.99.21: D-sorbitol dehydrogenase (acceptor)
EC 1.1.99.22: glycerol dehydrogenase (acceptor)
EC 1.1.99.23: Now EC 1.1.2.6, polyvinyl alcohol dehydrogenase (cytochrome)
EC 1.1.99.24: hydroxyacid-oxoacid transhydrogenase
EC 1.1.99.25: Now EC 1.1.5.8, quinate dehydrogenase (quinone),
EC 1.1.99.26: 3-hydroxycyclohexanone dehydrogenase
EC 1.1.99.27: (R)-pantolactone dehydrogenase (flavin)
EC 1.1.99.28: glucose-fructose oxidoreductase
EC 1.1.99.29: pyranose dehydrogenase (acceptor)
EC 1.1.99.30: 2-oxoacid reductase
EC 1.1.99.31: (S)-mandelate dehydrogenase
EC 1.1.99.32: L-sorbose 1-dehydrogenase
EC 1.1.99.33: Now EC 1.17.99.7, formate dehydrogenase (acceptor)
EC 1.1.99.34: now EC 1.1.98.2, glucose-6-phosphate dehydrogenase (coenzyme-F₄₂₀)
EC 1.1.99.35: soluble quinoprotein glucose dehydrogenase
EC 1.1.99.36: alcohol dehydrogenase (nicotinoprotein)
EC 1.1.99.37: methanol dehydrogenase (nicotinoprotein)
EC 1.1.99.38: 2-deoxy-scyllo-inosamine dehydrogenase (AdoMet-dependent)
EC 1.1.99.39: D-2-hydroxyglutarate dehydrogenase
EC 1.1.99.40: (R)-2-hydroxyglutarate—pyruvate transhydrogenase
EC 1.1.99.41: 3-hydroxy-1,2-didehydro-2,3-dihydrotabersonine reductase
EC 1.1.99.42: 4-pyridoxic acid dehydrogenase

EC 1.2 Acting on the aldehyde or oxo group of donors

EC 1.2.1 With NAD⁺ or NADP⁺ as acceptor

EC 1.2.1.1: deleted, replaced by EC 1.1.1.284, S-(hydroxymethyl)glutathione dehydrogenase and EC 4.4.1.22, S-(hydroxymethyl)glutathione synthase
EC 1.2.1.2: Now EC 1.17.1.9, formate dehydrogenase
EC 1.2.1.3: aldehyde dehydrogenase (NAD⁺)
EC 1.2.1.4: aldehyde dehydrogenase (NADP⁺)
EC 1.2.1.5: aldehyde dehydrogenase (NAD(P)⁺)
EC 1.2.1.6: deleted (was benzaldehyde dehydrogenase)
EC 1.2.1.7: benzaldehyde dehydrogenase (NADP⁺)
EC 1.2.1.8: betaine-aldehyde dehydrogenase
EC 1.2.1.9: glyceraldehyde-3-phosphate dehydrogenase (NADP⁺)
EC 1.2.1.10: acetaldehyde dehydrogenase (acetylating)
EC 1.2.1.11: aspartate-semialdehyde dehydrogenase
EC 1.2.1.12: glyceraldehyde-3-phosphate dehydrogenase (phosphorylating)
EC 1.2.1.13: glyceraldehyde-3-phosphate dehydrogenase (NADP⁺) (phosphorylating)
EC 1.2.1.14: Now EC 1.1.1.205, IMP dehydrogenase
EC 1.2.1.15: malonate-semialdehyde dehydrogenase
EC 1.2.1.16: succinate-semialdehyde dehydrogenase [NAD(P)⁺]
EC 1.2.1.17: glyoxylate dehydrogenase (acylating)
EC 1.2.1.18: malonate-semialdehyde dehydrogenase (acetylating)
EC 1.2.1.19: aminobutyraldehyde dehydrogenase
EC 1.2.1.20: glutarate-semialdehyde dehydrogenase
EC 1.2.1.21: glycolaldehyde dehydrogenase
EC 1.2.1.22: lactaldehyde dehydrogenase
EC 1.2.1.23: 2-oxoaldehyde dehydrogenase (NAD⁺)
EC 1.2.1.24: succinate-semialdehyde dehydrogenase (NAD⁺)
EC 1.2.1.25: branched-chain α-keto acid dehydrogenase system
EC 1.2.1.26: 2,5-dioxovalerate dehydrogenase
EC 1.2.1.27: methylmalonate-semialdehyde dehydrogenase (CoA-acylating)
EC 1.2.1.28: benzaldehyde dehydrogenase (NAD⁺)
EC 1.2.1.29: aryl-aldehyde dehydrogenase
EC 1.2.1.30: carboxylate reductase (NADP⁺)
EC 1.2.1.31: L-aminoadipate-semialdehyde dehydrogenase
EC 1.2.1.32: aminomuconate-semialdehyde dehydrogenase
EC 1.2.1.33: (R)-dehydropantoate dehydrogenase
EC 1.2.1.34: Now EC 1.1.1.131, mannuronate reductase
EC 1.2.1.35: Now EC 1.1.1.203, uronate dehydrogenase
EC 1.2.1.36: retinal dehydrogenase
EC 1.2.1.37: Now EC 1.17.1.4, xanthine dehydrogenase
EC 1.2.1.38: N-acetyl-γ-glutamyl-phosphate reductase
EC 1.2.1.39: phenylacetaldehyde dehydrogenase
EC 1.2.1.40: part of EC 1.14.13.15, cholestanetriol 26-monooxygenase
EC 1.2.1.41: glutamate-5-semialdehyde dehydrogenase
EC 1.2.1.42: hexadecanal dehydrogenase (acylating)
EC 1.2.1.43: Now EC 1.17.1.10, formate dehydrogenase (NADP⁺)
EC 1.2.1.44: cinnamoyl-CoA reductase
EC 1.2.1.45: Now EC 1.1.1.312, 2-hydroxy-4-carboxymuconate semialdehyde hemiacetal dehydrogenase
EC 1.2.1.46: formaldehyde dehydrogenase
EC 1.2.1.47: 4-trimethylammoniobutyraldehyde dehydrogenase
EC 1.2.1.48: long-chain-aldehyde dehydrogenase
EC 1.2.1.49: 2-oxoaldehyde dehydrogenase (NADP⁺)
EC 1.2.1.50: long-chain-fatty-acyl-CoA reductase
EC 1.2.1.51: pyruvate dehydrogenase (NADP⁺)
EC 1.2.1.52: oxoglutarate dehydrogenase (NADP⁺)
EC 1.2.1.53: 4-hydroxyphenylacetaldehyde dehydrogenase
EC 1.2.1.54: γ-guanidinobutyraldehyde dehydrogenase
EC 1.2.1.55: Now EC 1.1.1.279, (R)-3-hydroxyacid-ester dehydrogenase
EC 1.2.1.56: Now EC 1.1.1.280, (S)-3-hydroxyacid-ester dehydrogenase
EC 1.2.1.57: butanal dehydrogenase
EC 1.2.1.58: phenylglyoxylate dehydrogenase (acylating)
EC 1.2.1.59: glyceraldehyde-3-phosphate dehydrogenase (NAD(P)⁺)
EC 1.2.1.60: 5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase
EC 1.2.1.61: 4-hydroxymuconic-semialdehyde dehydrogenase
EC 1.2.1.62: 4-formylbenzenesulfonate dehydrogenase
EC 1.2.1.63: 6-oxohexanoate dehydrogenase
EC 1.2.1.64: 4-hydroxybenzaldehyde dehydrogenase (NAD⁺)
EC 1.2.1.65: salicylaldehyde dehydrogenase
EC 1.2.1.66: Now EC 1.1.1.306, S-(hydroxymethyl)mycothiol dehydrogenase]]
EC 1.2.1.67: vanillin dehydrogenase
EC 1.2.1.68: coniferyl-aldehyde dehydrogenase
EC 1.2.1.69: fluoroacetaldehyde dehydrogenase
EC 1.2.1.70: glutamyl-tRNA reductase
EC 1.2.1.71: succinylglutamate-semialdehyde dehydrogenase
EC 1.2.1.72: erythrose-4-phosphate dehydrogenase
EC 1.2.1.73: sulfoacetaldehyde dehydrogenase
EC 1.2.1.74: abieta-7,13-dien-18-al dehydrogenase
EC 1.2.1.75: malonyl CoA reductase (malonate semialdehyde-forming)
EC 1.2.1.76: succinate-semialdehyde dehydrogenase (acylating)
EC 1.2.1.77: 3,4-dehydroadipyl-CoA semialdehyde dehydrogenase (NADP⁺)
EC 1.2.1.78: 2-formylbenzoate dehydrogenase
EC 1.2.1.79: succinate-semialdehyde dehydrogenase (NADP⁺)
EC 1.2.1.80: long-chain acyl-[acyl-carrier-protein] reductase
EC 1.2.1.81: sulfoacetaldehyde dehydrogenase (acylating)
EC 1.2.1.82: β-apo-4′-carotenal oxygenase
EC 1.2.1.83: 3-succinoylsemialdehyde-pyridine dehydrogenase
EC 1.2.1.84: alcohol-forming fatty acyl-CoA reductase
EC 1.2.1.85: 2-hydroxymuconate-6-semialdehyde dehydrogenase
EC 1.2.1.86: geranial dehydrogenase
EC 1.2.1.87: propanal dehydrogenase (CoA-propanoylating)
EC 1.2.1.88: L-glutamate γ-semialdehyde dehydrogenase
EC 1.2.1.89: D-glyceraldehyde dehydrogenase (NADP⁺)
EC 1.2.1.90: glyceraldehyde-3-phosphate dehydrogenase [NAD(P)⁺]
EC 1.2.1.91: 3-oxo-5,6-dehydrosuberyl-CoA semialdehyde dehydrogenase
EC 1.2.1.92: 3,6-anhydro-α-L-galactose dehydrogenase
EC 1.2.1.93: formate dehydrogenase (NAD+, ferredoxin). Now EC 1.17.1.11, formate dehydrogenase (NAD⁺, ferredoxin) *
EC 1.2.1.94: farnesal dehydrogenase
EC 1.2.1.95: L-2-aminoadipate reductase
EC 1.2.1.96: 4-hydroxybenzaldehyde dehydrogenase (⁺+)
EC 1.2.1.97: 3-sulfolactaldehyde dehydrogenase
EC 1.2.1.98: 2-hydroxy-2-methylpropanal dehydrogenase
EC 1.2.1.99: 4-(γ-glutamylamino)butanal dehydrogenase
EC 1.2.1.100: 5-formyl-3-hydroxy-2-methylpyridine 4-carboxylic acid 5-dehydrogenase
EC 1.2.1.101: L-tyrosine reductase
EC 1.2.1.102: isopyridoxal dehydrogenase (5-pyridoxate-forming)
EC 1.2.1.103: [amino-group carrier protein]-6-phospho-L-2-aminoadipate reductase
EC 1.2.1.104: pyruvate dehydrogenase system
EC 1.2.1.105: 2-oxoglutarate dehydrogenase system
EC 1.2.1.106: [amino-group carrier protein]-5-phospho-L-glutamate reductase
EC 1.2.1.107: glyceraldehyde-3-phosphate dehydrogenase (arsenate-transferring)

EC 1.2.2 With a cytochrome as acceptor

EC 1.2.2.1: formate dehydrogenase (cytochrome)
EC 1.2.2.2: Now covered by EC 1.2.5.1, pyruvate dehydrogenase (quinone)
EC 1.2.2.3: Now EC 1.17.2.3, formate dehydrogenase (cytochrome-c-553)
EC 1.2.2.4: Now classified as EC 1.2.5.3, aerobic carbon monoxide dehydrogenase

EC 1.2.3 With oxygen as acceptor

EC 1.2.3.1: aldehyde oxidase
EC 1.2.3.2: Now EC 1.17.3.2, xanthine oxidase
EC 1.2.3.3: pyruvate oxidase
EC 1.2.3.4: oxalate oxidase
EC 1.2.3.5: glyoxylate oxidase
EC 1.2.3.6: pyruvate oxidase (CoA-acetylating)
EC 1.2.3.7: indole-3-acetaldehyde oxidase
EC 1.2.3.8: pyridoxal oxidase
EC 1.2.3.9: aryl-aldehyde oxidase
EC 1.2.3.10: deleted, activity due to EC 1.2.2.4 carbon-monoxide dehydrogenase (cytochrome b-561)
EC 1.2.3.11: retinal oxidase
EC 1.2.3.12: Now included with EC 1.2.3.1, aldehyde oxidase
EC 1.2.3.13: Now EC 1.14.13.82, vanillate monooxygenase
EC 1.2.3.14: Abscisic-aldehyde oxidase
EC 1.2.3.15: (methyl)glyoxal oxidase

EC 1.2.4 With a disulfide as acceptor

EC 1.2.4.1: pyruvate dehydrogenase (acetyl-transferring)
EC 1.2.4.2: oxoglutarate dehydrogenase (succinyl-transferring)
EC 1.2.4.3: Now included with EC 1.2.4.4, 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
EC 1.2.4.4: 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)

EC 1.2.5 With a quinone or similar compound as acceptor

EC 1.2.5.1: pyruvate dehydrogenase (quinone)
EC 1.2.5.2: aldehyde dehydrogenase (quinone)
EC 1.2.5.3: aerobic carbon monoxide dehydrogenase

EC 1.2.7 With an iron–sulfur protein as acceptor

EC 1.2.7.1: pyruvate synthase
EC 1.2.7.2: Now included with EC 1.2.7.1, pyruvate synthase.
EC 1.2.7.3: 2-oxoglutarate synthase
EC 1.2.7.4: anaerobic carbon monoxide dehydrogenase
EC 1.2.7.5: aldehyde ferredoxin oxidoreductase
EC 1.2.7.6: glyceraldehyde-3-phosphate dehydrogenase (ferredoxin)
EC 1.2.7.7: 3-methyl-2-oxobutanoate dehydrogenase (ferredoxin)
EC 1.2.7.8: indolepyruvate ferredoxin oxidoreductase
EC 1.2.7.9: deleted, identical to EC 1.2.7.3, 2-oxoglutarate synthase
EC 1.2.7.10: oxalate oxidoreductase
EC 1.2.7.11: 2-oxoacid oxidoreductase (ferredoxin)
EC 1.2.7.12: formylmethanofuran dehydrogenase

===EC 1.2.98: with other,known physiological acceptors===

EC 1.2.98.1: formaldehyde dismutase

===EC 1.2.99: With unknown physiological acceptors===

EC 1.2.99.1: Now EC 1.17.99.4, uracil/thymine dehydrogenase
EC 1.2.99.2: Now EC 1.2.7.4, carbon-monoxide dehydrogenase (ferredoxin)
EC 1.2.99.3: Now EC 1.2.5.2, aldehyde dehydrogenase (quinone)
EC 1.2.99.4: Now EC 1.2.98.1, formaldehyde dismutase
EC 1.2.99.5: Now EC 1.2.7.12, formylmethanofuran dehydrogenase
EC 1.2.99.6: carboxylate reductase
EC 1.2.99.7: aldehyde dehydrogenase (FAD-independent)
EC 1.2.99.8: glyceraldehyde dehydrogenase (FAD-containing)
EC 1.2.99.9: Now EC 1.17.98.3, formate dehydrogenase (coenzyme F₄₂₀)
EC 1.2.99.10: 4,4′-diapolycopenoate synthase

EC 1.3 Acting on the CH-CH group of donors

EC 1.3.1 With NAD⁺ or NADP⁺ as acceptor

EC 1.3.1.1: dihydrouracil dehydrogenase (NAD⁺)
EC 1.3.1.2: dihydropyrimidine dehydrogenase (NADP⁺)
EC 1.3.1.3: Δ⁴-3-oxosteroid 5β-reductase
EC 1.3.1.4: transferred to EC 1.3.1.22, 3-oxo-5α-steroid 4-dehydrogenase (NADP⁺)
EC 1.3.1.5: cucurbitacin Δ²³-reductase
EC 1.3.1.6: fumarate reductase (NADH)
EC 1.3.1.7: meso-tartrate dehydrogenase
EC 1.3.1.8: acyl-CoA dehydrogenase (NADP⁺)
EC 1.3.1.9: enoyl-[acyl-carrier-protein] reductase (NADH)
EC 1.3.1.10: enoyl-[acyl-carrier-protein] reductase (NADPH, Si-specific)
EC 1.3.1.11: 2-coumarate reductase
EC 1.3.1.12: prephenate dehydrogenase
EC 1.3.1.13: prephenate dehydrogenase (NADP⁺)
EC 1.3.1.14: dihydroorotate dehydrogenase (NAD⁺)
EC 1.3.1.15: dihydroorotate dehydrogenase (NADP⁺)
EC 1.3.1.16: β-nitroacrylate reductase
EC 1.3.1.17: 3-methyleneoxindole reductase
EC 1.3.1.18: kynurenate-7,8-dihydrodiol dehydrogenase
EC 1.3.1.19: cis-1,2-dihydrobenzene-1,2-diol dehydrogenase
EC 1.3.1.20: trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
EC 1.3.1.21: 7-dehydrocholesterol reductase
EC 1.3.1.22: 3-oxo-5α-steroid 4-dehydrogenase (NADP⁺)
EC 1.3.1.23: [[identical to ((EC 1.3.1.3)), ((cortisone b-reductase|Δ4-3-oxosteroid 5β-reductase))|identical to EC 1.3.1.3, Δ4-3-oxosteroid 5β-reductase]]
EC 1.3.1.24: biliverdin reductase
EC 1.3.1.25: 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase
EC 1.3.1.26: Now EC 1.17.1.8, 4-hydroxy-tetrahydrodipicolinate reductase
EC 1.3.1.27: 2-hexadecenal reductase
EC 1.3.1.28: 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase
EC 1.3.1.29: cis-1,2-dihydro-1,2-dihydroxynaphthalene dehydrogenase
EC 1.3.1.30: transferred to EC 1.3.1.22, 3-oxo-5α-steroid 4-dehydrogenase (NADP⁺)
EC 1.3.1.31: 2-enoate reductase
EC 1.3.1.32: maleylacetate reductase
EC 1.3.1.33: protochlorophyllide reductase
EC 1.3.1.34: 2,4-dienoyl-CoA reductase (NADPH)|2,4-dienoyl-CoA reductase [(2E)-enoyl-CoA-producing]
EC 1.3.1.35: Now EC 1.14.19.22, microsomal oleoyl-lipid 12-desaturase
EC 1.3.1.36: geissoschizine dehydrogenase
EC 1.3.1.37: cis-2-enoyl-CoA reductase (NADPH)
EC 1.3.1.38: trans-2-enoyl-CoA reductase (NADPH)
EC 1.3.1.39: trans-2-enoyl-CoA reductase (NADPH)
EC 1.3.1.40: 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate reductase
EC 1.3.1.41: xanthommatin reductase
EC 1.3.1.42: 12-oxophytodienoate reductase
EC 1.3.1.43: arogenate dehydrogenase
EC 1.3.1.44: trans-2-enoyl-CoA reductase (NAD⁺)
EC 1.3.1.45: 2′-hydroxyisoflavone reductase
EC 1.3.1.46: biochanin-A reductase
EC 1.3.1.47: α-santonin 1,2-reductase
EC 1.3.1.48: 13,14-dehydro-15-oxoprostaglandin 13-reductase
EC 1.3.1.49: cis-3,4-dihydrophenanthrene-3,4-diol dehydrogenase
EC 1.3.1.50: n Now EC 1.1.1.252 tetrahydroxynaphthalene reductase
EC 1.3.1.51: 2′-hydroxydaidzein reductase
EC 1.3.1.52: Now EC 1.3.8.5, 2-methyl-branched-chain-enoyl-CoA reductase
EC 1.3.1.53: (3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate dehydrogenase
EC 1.3.1.54: precorrin-6A reductase
EC 1.3.1.55: identical to EC 1.3.1.25, 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase
EC 1.3.1.56: cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase
EC 1.3.1.57: phloroglucinol reductase
EC 1.3.1.58: 2,3-dihydroxy-2,3-dihydro-p-cumate dehydrogenase
EC 1.3.1.59: There is no evidence that the enzyme exists
EC 1.3.1.60: dibenzothiophene dihydrodiol dehydrogenase
EC 1.3.1.61: identical to EC 1.3.1.53, (3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate dehydrogenase
EC 1.3.1.62: pimeloyl-CoA dehydrogenase
EC 1.3.1.63: Now EC 1.21.1.2, 2,4-dichlorobenzoyl-CoA reductase
EC 1.3.1.64: phthalate 4,5-cis-dihydrodiol dehydrogenase
EC 1.3.1.65: 5,6-dihydroxy-3-methyl-2-oxo-1,2,5,6-tetrahydroquinoline dehydrogenase
EC 1.3.1.66: cis-dihydroethylcatechol dehydrogenase
EC 1.3.1.67: cis-1,2-dihydroxy-4-methylcyclohexa-3,5-diene-1-carboxylate dehydrogenase
EC 1.3.1.68: 1,2-dihydroxy-6-methylcyclohexa-3,5-dienecarboxylate dehydrogenase
EC 1.3.1.69: zeatin reductase
EC 1.3.1.70: Δ¹⁴-sterol reductase
EC 1.3.1.71: Δ^24(24¹)-sterol reductase
EC 1.3.1.72: Δ²⁴-sterol reductase
EC 1.3.1.73: 1,2-dihydrovomilenine reductase
EC 1.3.1.74: 2-alkenal reductase [NAD(P)⁺]
EC 1.3.1.75: 3,8-divinyl protochlorophyllide a 8-vinyl-reductase (NADPH)
EC 1.3.1.76: precorrin-2 dehydrogenase
EC 1.3.1.77: anthocyanidin reductase [(2R,3R)-flavan-3-ol-forming]
EC 1.3.1.78: arogenate dehydrogenase (NADP⁺)
EC 1.3.1.79: arogenate dehydrogenase (NAD(P)⁺)
EC 1.3.1.80: Now classified as EC 1.3.7.12, red chlorophyll catabolite reductase
EC 1.3.1.81: (+)-pulegone reductase
EC 1.3.1.82: (-)-isopiperitenone reductase
EC 1.3.1.83: geranylgeranyl diphosphate reductase
EC 1.3.1.84: acrylyl-CoA reductase (NADPH)
EC 1.3.1.85: crotonyl-CoA carboxylase/reductase
EC 1.3.1.86: crotonyl-CoA reductase
EC 1.3.1.87: 3-(cis-5,6-dihydroxycyclohexa-1,3-dien-1-yl)propanoate dehydrogenase
EC 1.3.1.88: tRNA-dihydrouridine^16/17 synthase (NAD(P)⁺)
EC 1.3.1.89: tRNA-dihydrouridine⁴⁷ synthase (NAD(P)⁺)
EC 1.3.1.90: tRNA-dihydrouridine^20a/20b synthase (NAD(P)⁺)
EC 1.3.1.91: tRNA-dihydrouridine²⁰ synthase (NAD(P)⁺)
EC 1.3.1.92: artemisinic aldehyde Δ¹¹⁽¹³⁾-reductase
EC 1.3.1.93: very-long-chain enoyl-CoA reductase
EC 1.3.1.94: polyprenol reductase
EC 1.3.1.95: acrylyl-CoA reductase (NADH)
EC 1.3.1.96: Botryococcus squalene synthase
EC 1.3.1.97: botryococcene synthase
EC 1.3.1.98: Now known to be catalyzed by two different enzymes, EC 1.3.1.122, (S)-8-oxocitronellyl enol synthase, and EC 5.5.1.34, (+)-cis,trans-nepetalactol synthase
EC 1.3.1.100: chanoclavine-I aldehyde reductase
EC 1.3.1.101: 2,3-bis-O-geranylgeranyl-sn-glycerol 1-phosphate reductase [NAD(P)H]
EC 1.3.1.102: 2-alkenal reductase (NADP+)
EC 1.3.1.103: 2-haloacrylate reductase
EC 1.3.1.104: enoyl-[acyl-carrier-protein] reductase (NADPH)
EC 1.3.1.105: 2-methylene-furan-3-one reductase
EC 1.3.1.106: cobalt-precorrin-6A reductase
EC 1.3.1.107: sanguinarine reductase
EC 1.3.1.108: caffeoyl-CoA reductase
EC 1.3.1.109: butanoyl-CoA dehydrogenase complex (NAD⁺, ferredoxin)
EC 1.3.1.110: lactate dehydrogenase (NAD⁺,ferredoxin)
EC 1.3.1.111: geranylgeranyl-bacteriochlorophyllide a reductase
EC 1.3.1.112: anthocyanidin reductase [(2S)-flavan-3-ol-forming]
EC 1.3.1.113: (4-alkanoyl-5-oxo-2,5-dihydrofuran-3-yl)methyl phosphate reductase
EC 1.3.1.114: 3-dehydro-bile acid Δ^4,6-reductase
EC 1.3.1.115: 3-oxocholoyl-CoA 4-desaturase
EC 1.3.1.116: 7β-hydroxy-3-oxochol-24-oyl-CoA 4-desaturase
EC 1.3.1.117: hydroxycinnamoyl-CoA reductase
EC 1.3.1.118: meromycolic acid enoyl-[acyl-carrier-protein] reductase
EC 1.3.1.119: chlorobenzene dihydrodiol dehydrogenase
EC 1.3.1.120: cyclohexane-1-carbonyl-CoA reductase NADP⁺)
EC 1.3.1.121: 4-amino-4-deoxyprephenate dehydrogenase
EC 1.3.1.122: (S)-8-oxocitronellyl enol synthase
EC 1.3.1.123: 8-oxogeranial reductase
EC 1.3.1.124: 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing]

EC 1.3.2 With a cytochrome as acceptor

EC 1.3.2.1: now EC 1.3.99.2
EC 1.3.2.2: now EC 1.3.99.3
EC 1.3.2.3: galactonolactone dehydrogenase

EC 1.3.3 With oxygen as acceptor

EC 1.3.5 With a quinone or related compound as acceptor

EC 1.3.7 With an iron–sulfur protein as acceptor

EC 1.3.8 With a flavin as acceptor

EC 1.3.8.1: short-chain acyl-CoA dehydrogenase
EC 1.3.8.2: 4,4′-diapophytoene desaturase (4,4′-diapolycopene-forming)
EC 1.3.8.3: (R)-benzylsuccinyl-CoA dehydrogenase
EC 1.3.8.4: isovaleryl-CoA dehydrogenase
EC 1.3.8.5: 2-methyl-branched-chain-enoyl-CoA reductase
EC 1.3.8.6: glutaryl-CoA dehydrogenase (ETF)
EC 1.3.8.7: medium-chain acyl-CoA dehydrogenase
EC 1.3.8.8: long-chain acyl-CoA dehydrogenase
EC 1.3.8.9: very-long-chain acyl-CoA dehydrogenase
EC 1.3.8.10: cyclohex-1-ene-1-carbonyl-CoA dehydrogenase
EC 1.3.8.11: cyclohexane-1-carbonyl-CoA dehydrogenase (electron-transfer flavoprotein)
EC 1.3.8.12: (2S)-methylsuccinyl-CoA dehydrogenase
EC 1.3.8.13: crotonobetainyl-CoA reductase
EC 1.3.8.14: L-prolyl-[peptidyl-carrier protein] dehydrogenase
EC 1.3.8.15: 3-(aryl)acrylate reductase
EC 1.3.8.16: 2-amino-4-deoxychorismate dehydrogenase
EC 1.3.8.17: dehydro coenzyme F₄₂₀ reductase

EC 1.3.98 With other,known physiological acceptors

EC 1.3.98.1: dihydroorotate dehydrogenase (fumarate)
EC 1.3.98.2: Now EC 1.3.4.1, fumarate reductase (CoM/CoB)
EC 1.3.98.3: coproporphyrinogen dehydrogenase
EC 1.3.98.4: 5a,11a-dehydrotetracycline reductase
EC 1.3.98.5: hydrogen peroxide-dependent heme synthase
EC 1.3.98.6: AdoMet-dependent heme synthase
EC 1.3.98.7: [mycofactocin precursor peptide]-tyrosine decarboxylase

EC 1.3.99 With unknown physiological acceptors

EC 1.3.99.1: The activity is included in EC 1.3.5.1, succinate dehydrogenase (quinone)
EC 1.3.99.2: Now EC 1.3.8.1, butyryl-CoA dehydrogenase.
EC 1.3.99.3: now EC 1.3.8.7, medium-chain acyl-CoA dehydrogenase, EC 1.3.8.8, long-chain acyl-CoA dehydrogenase and EC 1.3.8.9, very-long-chain acyl-CoA dehydrogenase
EC 1.3.99.4: 3-oxosteroid 1-dehydrogenase
EC 1.3.99.5: 3-oxo-5α-steroid 4-dehydrogenase (acceptor)
EC 1.3.99.6: 3-oxo-5β-steroid 4-dehydrogenase
EC 1.3.99.7: Now EC 1.3.8.6, glutaryl-CoA dehydrogenase
EC 1.3.99.8: 2-furoyl-CoA dehydrogenase
EC 1.3.99.9: Now EC 1.21.99.1, β-cyclopiazonate dehydrogenase
EC 1.3.99.10: Now EC 1.3.8.4, isovaleryl-CoA dehydrogenase
EC 1.3.99.11: transferred to EC 1.3.5.2, dihydroorotate dehydrogenase
EC 1.3.99.12: Now classified as EC 1.3.8.5, 2-methyl-branched-chain-enoyl-CoA reductase
EC 1.3.99.13: Now EC 1.3.8.8, long-chain-acyl-CoA dehydrogenase
EC 1.3.99.14: cyclohexanone dehydrogenase
EC 1.3.99.15: Now EC 1.3.7.8
EC 1.3.99.16: isoquinoline 1-oxidoreductase
EC 1.3.99.17: quinoline 2-oxidoreductase
EC 1.3.99.18: quinaldate 4-oxidoreductase
EC 1.3.99.19: quinoline-4-carboxylate 2-oxidoreductase
EC 1.3.99.20: Now EC 1.3.7.9, 4-hydroxybenzoyl-CoA reductase
EC 1.3.99.21: Now EC 1.3.8.3, (R)-benzylsuccinyl-CoA dehydrogenase
EC 1.3.99.22: Now EC 1.3.98.3, coproporphyrinogen dehydrogenase
EC 1.3.99.23: all-trans-retinol 13,14-reductase
EC 1.3.99.24: Now EC 1.3.8.16, 2-amino-4-deoxychorismate dehydrogenase
EC 1.3.99.25: carvone reductase
EC 1.3.99.26: all-trans-ζ-carotene desaturase
EC 1.3.99.27: 1-hydroxycarotenoid 3,4-desaturase
EC 1.3.99.28: phytoene desaturase (neurosporene-forming)
EC 1.3.99.29: phytoene desaturase (zeta-carotene-forming)
EC 1.3.99.30: phytoene desaturase (3,4-didehydrolycopene-forming)
EC 1.3.99.31: phytoene desaturase (lycopene-forming)
EC 1.3.99.32: glutaryl-CoA dehydrogenase (non-decarboxylating)
EC 1.3.99.33: urocanate reductase
EC 1.3.99.34: Now classified as EC 1.3.7.11, 2,3-bis-O-geranylgeranyl-sn-glycero-phospholipid reductase
EC 1.3.99.35: Now EC 1.3.7.15, chlorophyllide a reductase *
EC 1.3.99.36: cypemycin cysteine dehydrogenase (decarboxylating)
EC 1.3.99.37: 1-hydroxy-2-isopentenylcarotenoid 3,4-desaturase
EC 1.3.99.38: menaquinone-9 β-reductase
EC 1.3.99.39: carotenoid φ-ring synthase
EC 1.3.99.40: carotenoid χ-ring synthase

EC 1.4 Acting on the CH-NH₂ group of donors

EC 1.4.1 With NAD⁺ or NADP⁺ as acceptor

EC 1.4.1.1: alanine dehydrogenase
EC 1.4.1.2: glutamate dehydrogenase
EC 1.4.1.3: glutamate dehydrogenase (NAD(P)⁺)
EC 1.4.1.4: glutamate dehydrogenase (NADP⁺)
EC 1.4.1.5: L-amino-acid dehydrogenase
EC 1.4.1.6: deleted, Now included with EC 1.21.4.1, D-proline reductase (dithiol)
EC 1.4.1.7: serine 2-dehydrogenase
EC 1.4.1.8: valine dehydrogenase (NADP⁺)
EC 1.4.1.9: leucine dehydrogenase
EC 1.4.1.10: glycine dehydrogenase
EC 1.4.1.11: L-erythro-3,5-diaminohexanoate dehydrogenase
EC 1.4.1.12: 2,4-diaminopentanoate dehydrogenase
EC 1.4.1.13: glutamate synthase (NADPH)
EC 1.4.1.14: glutamate synthase (NADH)
EC 1.4.1.15: lysine dehydrogenase
EC 1.4.1.16: diaminopimelate dehydrogenase
EC 1.4.1.17: N-methylalanine dehydrogenase
EC 1.4.1.18: lysine 6-dehydrogenase
EC 1.4.1.19: tryptophan dehydrogenase
EC 1.4.1.20: phenylalanine dehydrogenase
EC 1.4.1.21: aspartate dehydrogenase
EC 1.4.1.22: there is no overall consumption of NAD⁺ during the reaction. As a result, transfer of the enzyme from EC 4.3.1.12 was not necessary and EC 1.4.1.22 was withdrawn before being made official
EC 1.4.1.23: valine dehydrogenase (NAD⁺)
EC 1.4.1.24: 3-dehydroquinate synthase II
EC 1.4.1.25: L-arginine dehydrogenase
EC 1.4.1.26: 2,4-diaminopentanoate dehydrogenase (NAD⁺)
EC 1.4.1.27: glycine cleavage system

EC 1.4.2 With a cytochrome as acceptor

EC 1.4.2.1: glycine dehydrogenase (cytochrome)

EC 1.4.3 With oxygen as acceptor

EC 1.4.3.1: D-aspartate oxidase
EC 1.4.3.2: L-amino-acid oxidase
EC 1.4.3.3: D-amino-acid oxidase
EC 1.4.3.4: monoamine oxidase
EC 1.4.3.5: pyridoxal 5′-phosphate synthase
EC 1.4.3.6: replaced by two enzymes, EC 1.4.3.21 (primary-amine oxidase) and EC 1.4.3.22 (diamine oxidase)
EC 1.4.3.7: D-glutamate oxidase
EC 1.4.3.8: ethanolamine oxidase
EC 1.4.3.9: Now included with EC 1.4.3.4 amine oxidase (flavin-containing)
EC 1.4.3.10: putrescine oxidase
EC 1.4.3.11: L-glutamate oxidase
EC 1.4.3.12: cyclohexylamine oxidase
EC 1.4.3.13: protein-lysine 6-oxidase
EC 1.4.3.14: L-lysine oxidase
EC 1.4.3.15: D-glutamate(D-aspartate) oxidase
EC 1.4.3.16: L-aspartate oxidase
EC 1.4.3.17: Now EC 1.3.3.10, tryptophan α,β-oxidase
EC 1.4.3.18: Not approved as the enzyme was shown to be a dehydrogenase and not an oxidase (see EC 1.5.99.12, cytokinin dehydrogenase)
EC 1.4.3.19: glycine oxidase
EC 1.4.3.20: L-lysine 6-oxidase
EC 1.4.3.21: primary-amine oxidase
EC 1.4.3.22: diamine oxidase
EC 1.4.3.23: 7-chloro-L-tryptophan oxidase
EC 1.4.3.24: pseudooxynicotine oxidase
EC 1.4.3.25: L-arginine oxidase
EC 1.4.3.26: pre-mycofactocin synthase

EC 1.4.4 With a disulfide as acceptor

EC 1.4.4.1: Now EC 1.21.4.1, D-proline reductase (dithiol)
EC 1.4.4.2: glycine dehydrogenase (aminomethyl-transferring)

EC 1.4.5 With a quinone or other compound as acceptor

EC 1.4.5.1: D-amino acid dehydrogenase (quinone)

EC 1.4.7 With an iron–sulfur protein as acceptor

EC 1.4.7.1: glutamate synthase (ferredoxin)

EC 1.4.9 With a copper protein as acceptor

EC 1.4.98 With other, known physiological acceptors

EC 1.4.98.1: NOW 1.4.9.1 methylamine dehydrogenase (amicyanin)

EC 1.4.99 With unknown physiological acceptors

EC 1.4.99.1: Now EC 1.4.99.6, D-arginine dehydrogenase
EC 1.4.99.2: taurine dehydrogenase
EC 1.4.99.3: Now EC 1.4.9.1, methylamine dehydrogenase (amicyanin)
EC 1.4.99.4: Now EC 1.4.9.2, aralkylamine dehydrogenase (azurin)
EC 1.4.99.5: glycine dehydrogenase (cyanide-forming)
EC 1.4.99.6: D-arginine dehydrogenase

EC 1.5 Acting on the CH-NH group of donors

EC 1.5.1 With NAD⁺ or NADP⁺ as acceptor

EC 1.5.1.1: 1-piperideine-2-carboxylate/1-pyrroline-2-carboxylate reductase [NAD(P)H
EC 1.5.1.2: pyrroline-5-carboxylate reductase
EC 1.5.1.3: dihydrofolate reductase
EC 1.5.1.4: Now included with EC 1.5.1.3 dihydrofolate reductase
EC 1.5.1.5: methylenetetrahydrofolate dehydrogenase (NADP⁺)
EC 1.5.1.6: formyltetrahydrofolate dehydrogenase
EC 1.5.1.7: saccharopine dehydrogenase (NAD⁺, L-lysine-forming)
EC 1.5.1.8: saccharopine dehydrogenase (NADP⁺, L-lysine-forming)
EC 1.5.1.9: saccharopine dehydrogenase (NAD⁺, L-glutamate-forming)
EC 1.5.1.10: saccharopine dehydrogenase (NADP⁺, L-glutamate-forming)
EC 1.5.1.11: D-octopine dehydrogenase
EC 1.5.1.12: Now EC 1.2.1.88, L-glutamate γ-semialdehyde dehydrogenase
EC 1.5.1.13: Now EC 1.17.1.5, nicotinate dehydrogenase
EC 1.5.1.14: Now included with EC 1.5.1.21 Δ¹-piperideine-2-carboxylate reductase
EC 1.5.1.15: methylenetetrahydrofolate dehydrogenase (NAD⁺)
EC 1.5.1.16: D-lysopine dehydrogenase
EC 1.5.1.17: alanopine dehydrogenase
EC 1.5.1.18: ephedrine dehydrogenase
EC 1.5.1.19: D-nopaline dehydrogenase
EC 1.5.1.20: methylenetetrahydrofolate reductase (NAD(P)H)
EC 1.5.1.21: 1-piperideine-2-carboxylate/1-pyrroline-2-carboxylate reductase (NADPH)
EC 1.5.1.22: strombine dehydrogenase
EC 1.5.1.23: tauropine dehydrogenase
EC 1.5.1.24: N⁵-(carboxyethyl)ornithine synthase
EC 1.5.1.25: thiomorpholine-carboxylate dehydrogenase
EC 1.5.1.26: β-alanopine dehydrogenase
EC 1.5.1.27: 1,2-dehydroreticulinium reductase (NADPH)
EC 1.5.1.28: opine dehydrogenase
EC 1.5.1.29: Now covered by EC 1.5.1.38 [FMN reductase (NADPH)], EC 1.5.1.39 [FMN reductase [NAD(P)H])] and EC 1.5.1.41 (riboflavin reductase [NAD(P)H])
EC 1.5.1.30: flavin reductase (NADPH)
EC 1.5.1.31: berberine reductase
EC 1.5.1.32: vomilenine reductase
EC 1.5.1.33: pteridine reductase
EC 1.5.1.34: 6,7-dihydropteridine reductase
EC 1.5.1.35: identical to EC 1.2.1.19, aminobutyraldehyde dehydrogenase, as the substrates 1-pyrroline and 4-aminobutanal are interconvertible
EC 1.5.1.36: flavin reductase (NADH)
EC 1.5.1.37: FAD reductase (NADH)
EC 1.5.1.38: FMN reductase (NADPH)
EC 1.5.1.39: FMN reductase (NAD(P)H)
EC 1.5.1.40: 8-hydroxy-5-deazaflavin:NADPH oxidoreductase
EC 1.5.1.41: riboflavin reductase (NAD(P)H)
EC 1.5.1.42: FMN reductase (NADH)
EC 1.5.1.43: carboxynorspermidine synthase
EC 1.5.1.44: festuclavine dehydrogenase
EC 1.5.1.45: FAD reductase (NAD(P)H)
EC 1.5.1.46: agroclavine dehydrogenase
EC 1.5.1.47: dihydromethanopterin reductase [NAD(P)⁺]
EC 1.5.1.48: 2-methyl-1-pyrroline reductase
EC 1.5.1.49: 1-pyrroline-2-carboxylate reductase [NAD(P)H]
EC 1.5.1.50: dihydromonapterin reductase
EC 1.5.1.51: N-[(2S)-2-amino-2-carboxyethyl]-L-lutamate dehydrogenase
EC 1.5.1.52: staphylopine dehydrogenase
EC 1.5.1.53: methylenetetrahydrofolate reductase (NADPH)
EC 1.5.1.54: methylenetetrahydrofolate reductase (NADH)

EC 1.5.3 With oxygen as acceptor

EC 1.5.3.1: sarcosine oxidase
EC 1.5.3.2: N-methyl-L-amino-acid oxidase
EC 1.5.3.3: deleted
EC 1.5.3.4: N⁶-methyl-lysine oxidase
EC 1.5.3.5: (S)-6-hydroxynicotine oxidase
EC 1.5.3.6: (R)-6-hydroxynicotine oxidase
EC 1.5.3.7: L-pipecolate oxidase
EC 1.5.3.8: Now included with EC 1.3.3.8, tetrahydroberberine oxidase
EC 1.5.3.9: Now EC 1.21.3.3, reticuline oxidase
EC 1.5.3.10: dimethylglycine oxidase
EC 1.5.3.11: Now included with EC 1.5.3.13 (N¹-acetylpolyamine oxidase), EC 1.5.3.14 (polyamine oxidase (propane-1,3-diamine-forming)), EC 1.5.3.15 (N⁸-acetylspermidine oxidase (propane-1,3-diamine-forming)), EC 1.5.3.16 (spermine oxidase) and EC 1.5.3.17 (non-specific polyamine oxidase)
EC 1.5.3.12: dihydrobenzophenanthridine oxidase
EC 1.5.3.13: N¹-acetylpolyamine oxidase
EC 1.5.3.14: polyamine oxidase (propane-1,3-diamine-forming)
EC 1.5.3.15: N⁸-acetylspermidine oxidase (propane-1,3-diamine-forming)
EC 1.5.3.16: spermine oxidase
EC 1.5.3.17: non-specific polyamine oxidase
EC 1.5.3.18: L-saccharopine oxidase
EC 1.5.3.19: 4-methylaminobutanoate oxidase (formaldehyde-forming)
EC 1.5.3.20: N-alkylglycine oxidase
EC 1.5.3.21: 4-methylaminobutanoate oxidase (methylamine-forming)
EC 1.5.3.22: coenzyme F₄₂₀H₂ oxidase
EC 1.5.3.23: glyphosate oxidoreductase

EC 1.5.4 With a disulfide as acceptor

EC 1.5.4.1: pyrimidodiazepine synthase

EC 1.5.5 With a quinone or similar compound as acceptor

EC 1.5.5.1: electron-transferring-flavoprotein dehydrogenase
EC 1.5.5.2: proline dehydrogenase
EC 1.5.5.3: hydroxyproline dehydrogenase

EC 1.5.7 With an iron–sulfur protein as acceptor

EC 1.5.8 With a flavin or flavoprotein as acceptor

EC 1.5.98 With other, known, physiological acceptors

EC 1.5.98.1: ethylenetetrahydromethanopterin dehydrogenase
EC 1.5.98.2: 5,10-methylenetetrahydromethanopterin reductase
EC 1.5.98.3: coenzyme F₄₂₀:methanophenazine dehydrogenase

EC 1.5.99 With unknown physiological acceptors

EC 1.5.99.1: Now EC 1.5.8.3, sarcosine dehydrogenase
EC 1.5.99.2: Now EC 1.5.8.4, dimethylglycine dehydrogenase
EC 1.5.99.3: L-pipecolate dehydrogenase
EC 1.5.99.4: nicotine dehydrogenase
EC 1.5.99.5: methylglutamate dehydrogenase
EC 1.5.99.6: spermidine dehydrogenase
EC 1.5.99.7: Now EC 1.5.8.2, trimethylamine dehydrogenase
EC 1.5.99.8: Now EC 1.5.5.2, proline dehydrogenase
EC 1.5.99.9: transferred to EC 1.5.98.1, methylenetetrahydromethanopterin dehydrogenase
EC 1.5.99.10: Now EC 1.5.8.1, dimethylamine dehydrogenase
EC 1.5.99.11: transferred to EC 1.5.98.2, 5,10-methylenetetrahydromethanopterin reductase
EC 1.5.99.12: cytokinin dehydrogenase
EC 1.5.99.13: D-proline dehydrogenase
EC 1.5.99.14: 6-hydroxypseudooxynicotine dehydrogenase
EC 1.5.99.15: dihydromethanopterin reductase (acceptor)

EC 1.6 Acting on NADH or NADPH

EC 1.6.1 With NAD or NADP as acceptor

EC 1.6.2 With a heme protein as acceptor

EC 1.6.2.1: now EC 1.6.99.3 NADH dehydrogenase
EC 1.6.2.2: cytochrome-b₅ reductase
EC 1.6.2.3: deleted
EC 1.6.2.4: NADPH—hemoprotein reductase
EC 1.6.2.5: NADPH—cytochrome-c₂ reductase
EC 1.6.2.6: leghemoglobin reductase

EC 1.6.3 With oxygen as acceptor

EC 1.6.3.1: NAD(P)H oxidase (H₂O₂-forming)
EC 1.6.3.2: NAD(P)H oxidase (H₂O-forming)
EC 1.6.3.3: NADH oxidase (H₂O₂-forming)
EC 1.6.3.4: NADH oxidase (H₂O-forming)
EC 1.6.3.5: renalase

EC 1.6.4 With a disulfide as acceptor (deleted sub-class)

EC 1.6.4.1: now EC 1.8.1.6 cystine reductase
EC 1.6.4.2: now EC 1.8.1.7 glutathione-disulfide reductase
EC 1.6.4.3: now EC 1.8.1.4 dihydrolipoyl dehydrogenase
EC 1.6.4.4: now EC 1.8.1.8 protein-disulfide reductase
EC 1.6.4.5: now EC 1.8.1.9 thioredoxin-disulfide reductase
EC 1.6.4.6: now EC 1.8.1.10 CoA-glutathione reductase
EC 1.6.4.7: now EC 1.8.1.11 asparagusate reductase
EC 1.6.4.8: now EC 1.8.1.12 trypanothione-disulfide reductase
EC 1.6.4.9: now EC 1.8.1.13 bis-γ-glutamylcystine reductase
EC 1.6.4.10: now EC 1.8.1.14 CoA-disulfide reductase

EC 1.6.5 With a quinone or similar compound as acceptor

EC 1.6.5.1: deleted
EC 1.6.5.2: NAD(P)H dehydrogenase (quinone)
EC 1.6.5.3: now EC 7.1.1.2 NADH:ubiquinone reductase (H⁺-translocating)
EC 1.6.5.4: monodehydroascorbate reductase (NADH)
EC 1.6.5.5: NADPH:quinone reductase
EC 1.6.5.6: p-benzoquinone reductase (NADPH)
EC 1.6.5.7: 2-hydroxy-1,4-benzoquinone reductase
EC 1.6.5.8: Now EC 7.2.1.1, NADH:ubiquinone reductase (Na⁺-transporting)
EC 1.6.5.9: NADH:ubiquinone reductase (non-electrogenic)
EC 1.6.5.10: NADPH dehydrogenase (quinone)
EC 1.6.5.11: [[Identical to EC 1.6.5.9, NADH:quinone reductase (non-electrogenic)]]
EC 1.6.5.12: demethylphylloquinone reductase

EC 1.6.6 With a nitrogenous group as acceptor

EC 1.6.6.1: Now EC 1.7.1.1, nitrate reductase (NADH)
EC 1.6.6.2: Now EC 1.7.1.2, nitrate reductase [NAD(P)H]
EC 1.6.6.3: Now EC 1.7.1.3, nitrate reductase (NADPH)
EC 1.6.6.4: Now EC 1.7.1.4, nitrite reductase [NAD(P)H]
EC 1.6.6.5: Now EC 1.7.2.1, nitrite reductase (NO-forming)
EC 1.6.6.6: Now EC 1.7.1.5, hyponitrite reductase
EC 1.6.6.7: Now EC 1.7.1.6, azobenzene reductase
EC 1.6.6.8: Now EC 1.7.1.7, GMP reductase
EC 1.6.6.9: Now known to be catalysed by EC 1.7.2.3, trimethylamine-N-oxide reductase
EC 1.6.6.10: Now EC 1.7.1.9, nitroquinoline-N-oxide reductase]
EC 1.6.6.11: Now EC 1.7.1.10, hydroxylamine reductase (NADH)
EC 1.6.6.12: Now EC 1.7.1.11, 4-(dimethylamino)phenylazoxybenzene reductase
EC 1.6.6.13: Now EC 1.7.1.12, N-hydroxy-2-acetamidofluorene reductase

EC 1.6.7 With an iron–sulfur protein as acceptor (deleted sub-subclass)

EC 1.6.7.1: now EC 1.18.1.2 ferredoxin—NADP⁺ reductase
EC 1.6.7.2: now EC 1.18.1.1 rubredoxin—NAD⁺ reductase
EC 1.6.7.3: now EC 1.18.1.3 ferredoxin—NAD⁺ reductase

EC 1.6.8 With a flavin as acceptor (deleted sub-subclass)

EC 1.6.8.1: Now EC 1.5.1.29 FMN reductase
EC 1.6.8.2: Now EC 1.5.1.30 flavin reductase

EC 1.6.99 With unknown physiological acceptors

EC 1.6.99.1: NADPH dehydrogenase
EC 1.6.99.2: Now EC 1.6.5.2, NAD(P)H dehydrogenase (quinone
EC 1.6.99.3: [[The activity is covered by EC 7.1.1.2, NADH:ubiquinone reductase (H+-translocating)|The activity is covered by EC 7.1.1.2, NADH:ubiquinone reductase (H⁺-translocating)]]
EC 1.6.99.4: Now EC 1.18.1.2, ferredoxin—NADP⁺ reductase
EC 1.6.99.5: Now EC 1.6.5.11, NADH dehydrogenase (quinone)
EC 1.6.99.6: Now EC 1.6.5.10, NADPH dehydrogenase (quinone)
EC 1.6.99.7: Now EC 1.5.1.34, 6,7-dihydropteridine reductase
EC 1.6.99.8: Deleted
EC 1.6.99.9: Now EC 1.16.1.4, cob(II)alamin reductase
EC 1.6.99.10: included in EC 1.5.1.34, 6,7-dihydropteridine reductase
EC 1.6.99.11: Deleted
EC 1.6.99.12: Now EC 1.16.1.6, cyanocobalamin reductase (cyanide-eliminating)
EC 1.6.99.13: Now EC 1.16.1.7, ferric-chelate reductase

EC 1.7 Acting on other nitrogenous compounds as donors

EC 1.7.1 With NAD⁺ or NADP⁺ as acceptor

EC 1.7.2 With a cytochrome as acceptor

EC 1.7.3 With oxygen as acceptor

EC 1.7.3.1: nitroalkane oxidase
EC 1.7.3.2: acetylindoxyl oxidase
EC 1.7.3.3: factor-independent urate hydroxylase
EC 1.7.3.4: Now covered by EC 1.7.2.6, hydroxylamine dehydrogenase, and EC 1.7.3.6, hydroxylamine oxidase (cytochrome)
EC 1.7.3.5: 3-aci-nitropropanoate oxidase
EC 1.7.3.6: hydroxylamine oxidase (cytochrome)

EC 1.7.5 With a quinone or similar compound as acceptor

EC 1.7.6 With a nitrogenous group as acceptor

EC 1.7.6.1: nitrite dismutase

EC 1.7.7 With an iron–sulfur protein as acceptor

EC 1.7.99 With other acceptors

EC 1.7.99.1: hydroxylamine reductase
EC 1.7.99.2: deleted: reaction may have been due to the combined action of EC 1.7.99.6 nitrous-oxide reductase and EC 1.7.99.7 nitric-oxide reductase
EC 1.7.99.3: Now included with EC 1.7.2.1, nitrite reductase (NO-forming)
EC 1.7.99.4: Now EC 1.7.1.1, nitrate reductase (NADH), EC 1.7.1.2, nitrate reductase [NAD(P)H], EC 1.7.1.3, nitrate reductase (NADPH), EC 1.7.5.1, nitrate reductase (quinone), EC 1.7.7.2, nitrate reductase (ferredoxin) and EC 1.9.6.1, nitrate reductase (cytochrome)
EC 1.7.99.5: Now included with EC 1.5.1.20, methylenetetrahydrofolate reductase [NAD(P)H]
EC 1.7.99.6: Now EC 1.7.2.4 nitrous-oxide reductase
EC 1.7.99.7: Now EC 1.7.2.5 nitric oxide reductase (cytochrome c)
EC 1.7.99.8: hydroxylamine oxidoreductase
EC 1.7.99.8: Now classified as EC 1.7.2.8, hydrazine dehydrogenase

EC 1.8 Acting on a sulfur group of donors

EC 1.8.1 With NAD⁺ or NADP⁺ as acceptor

EC 1.8.2 With a cytochrome as acceptor

EC 1.8.3 With oxygen as acceptor

EC 1.8.4 With a disulfide as acceptor

EC 1.8.4.1: glutathione—homocystine transhydrogenase
EC 1.8.4.2: protein-disulfide reductase (glutathione)
EC 1.8.4.3: glutathione—CoA-glutathione transhydrogenase
EC 1.8.4.4: glutathione—cystine transhydrogenase
EC 1.8.4.5: Now EC 1.8.4.13, L-methionine (S)-S-oxide reductase and EC 1.8.4.14, L-methionine (R)-S-oxide reductase
EC 1.8.4.6: [[due to EC 1.8.4.11, peptide-methionine (S)-S-oxide reductase|due to EC 1.8.4.11, peptide-methionine (S)-S-oxide reductase]]
EC 1.8.4.7: enzyme-thiol transhydrogenase (glutathione-disulfide)
EC 1.8.4.8: phosphoadenylyl-sulfate reductase (thioredoxin)
EC 1.8.4.9: adenylyl-sulfate reductase (glutathione)
EC 1.8.4.10: adenylyl-sulfate reductase (thioredoxin)
EC 1.8.4.11: peptide-methionine (S)-S-oxide reductase
EC 1.8.4.12: peptide-methionine (R)-S-oxide reductase
EC 1.8.4.13: L-methionine (S)-S-oxide reductase
EC 1.8.4.14: L-methionine (R)-S-oxide reductase
EC 1.8.4.15: protein dithiol oxidoreductase (disulfide-forming)
EC 1.8.4.16: thioredoxin:protein disulfide reductase

EC 1.8.5 With a quinone or similar compound as acceptor

EC 1.8.6 With a nitrogenous group as acceptor (deleted sub-subclass)

EC 1.8.6.1: Now included with EC 2.5.1.18 glutathione transferase

EC 1.8.7 With an iron–sulfur protein as acceptor

EC 1.8.98 With other, known, acceptors

EC 1.8.99 With other acceptors

EC 1.8.99.1: Now covered by EC 1.8.1.2, assimilatory sulfite reductase (NADPH) and EC 1.8.7.1, assimilatory sulfite reductase (ferredoxin)
EC 1.8.99.2: adenylyl-sulfate reductase
EC 1.8.99.3: [[an in vitro artifact of EC 1.8.99.5, dissimilatory sulfite reductase|an in vitro artifact of EC 1.8.99.5, dissimilatory sulfite reductase]]
EC 1.8.99.4: Now EC 1.8.4.8, phosphoadenylyl-sulfate reductase (thioredoxin)
EC 1.8.99.5: dissimilatory sulfite reductase

EC 1.9 Acting on a heme group of donors

EC 1.9.3 With oxygen as acceptor

EC 1.9.3.1: Now EC 7.1.1.9, cytochrome-c oxidase
EC 1.9.3.2: Now included with EC 1.7.2.1, nitrite reductase (NO-forming)

EC 1.9.6 With a nitrogenous group as acceptor

EC 1.9.6.1: nitrate reductase (cytochrome)

EC 1.9.98 With other, known, physiological acceptors

EC 1.9.98.1: iron—cytochrome-c reductase

EC 1.9.99 With other acceptors

EC 1.9.99.1: Now EC 1.9.98.1, iron—cytochrome-c reductase

EC 1.10 Acting on diphenols and related substances as donors

EC 1.10.1 With NAD⁺ or NADP⁺ as acceptor

EC 1.10.1.1: trans-acenaphthene-1,2-diol dehydrogenase

EC 1.10.2 With a cytochrome as acceptor

EC 1.10.2.1: [[The activity is covered by EC 7.2.1.3, ascorbate ferrireductase (transmembrane)]]
EC 1.10.2.2: Now EC 7.1.1.8, quinol—cytochrome-c reductase

EC 1.10.3 With oxygen as acceptor

EC 1.10.3.1: catechol oxidase
EC 1.10.3.2: laccase
EC 1.10.3.3: L-ascorbate oxidase
EC 1.10.3.4: o-aminophenol oxidase
EC 1.10.3.5: 3-hydroxyanthranilate oxidase
EC 1.10.3.6: rifamycin-B oxidase
EC 1.10.3.7: Now EC 1.21.3.4, sulochrin oxidase [(+)-bisdechlorogeodin-forming]
EC 1.10.3.8: Now EC 1.21.3.5, sulochrin oxidase [(-)-bisdechlorogeodin-forming]
EC 1.10.3.9: photosystem II
EC 1.10.3.10: Now EC 7.1.1.3, ubiquinol oxidase (H⁺-transporting)
EC 1.10.3.11: ubiquinol oxidase (non-electrogenic)
EC 1.10.3.12: Now EC 7.1.1.5, menaquinol oxidase (H⁺-transporting)
EC 1.10.3.13: Now EC 7.1.1.4, caldariellaquinol oxidase (H⁺-transporting)
EC 1.10.3.14: Now EC 7.1.1.7, ubiquinol oxidase (electrogenic, proton-motive force generating)
EC 1.10.3.15: grixazone synthase
EC 1.10.3.16: dihydrophenazinedicarboxylate synthase
EC 1.10.3.17: superoxide oxidase

EC 1.10.5 With a quinone or related compound as acceptor

EC 1.10.5.1: ribosyldihydronicotinamide dehydrogenase (quinone)

EC 1.10.9 With a copper protein as acceptor

EC 1.10.9.1: Now EC 7.1.1.6, plastoquinol—plastocyanin reductase

EC 1.10.99 With unknown physiological acceptors

EC 1.10.99.1: Now EC 1.10.9.1 plastoquinol—plastocyanin reductase
EC 1.10.99.2: Now EC 1.10.5.1 ribosyldihydronicotinamide dehydrogenase (quinone)
EC 1.10.99.3: Now EC 1.23.5.1 violaxanthin de-epoxidase

EC 1.11 Acting on a peroxide as acceptor

EC 1.11.1 Peroxidases

EC 1.11.1.1: NADH peroxidase
EC 1.11.1.2: NADPH peroxidase
EC 1.11.1.3: fatty-acid peroxidase
EC 1.11.1.4: Now EC 1.13.11.11 EC 1.13.11.11 tryptophan 2,3-dioxygenase
EC 1.11.1.5: cytochrome-c peroxidase
EC 1.11.1.6: catalase
EC 1.11.1.7: peroxidase
EC 1.11.1.8: iodide peroxidase
EC 1.11.1.9: glutathione peroxidase
EC 1.11.1.10: chloride peroxidase
EC 1.11.1.11: L-ascorbate peroxidase
EC 1.11.1.12: phospholipid-hydroperoxide glutathione peroxidase
EC 1.11.1.13: manganese peroxidase
EC 1.11.1.14: lignin peroxidase
EC 1.11.1.15: Now described by EC 1.11.1.24, thioredoxin-dependent peroxiredoxin; EC 1.11.1.25, glutaredoxin-dependent peroxiredoxin; EC 1.11.1.26, NADH-dependent peroxiredoxin; EC 1.11.1.27, glutathione-dependent peroxiredoxin; EC 1.11.1.28, lipoyl-dependent peroxiredoxin; and EC 1.11.1.29, mycoredoxin-dependent peroxiredoxin
EC 1.11.1.16: versatile peroxidase
EC 1.11.1.17: glutathione amide-dependent peroxidase
EC 1.11.1.18: bromide peroxidase
EC 1.11.1.19: dye decolorizing peroxidase
EC 1.11.1.20: prostamide/prostaglandin F_2α synthase
EC 1.11.1.21: catalase-peroxidase
EC 1.11.1.22: hydroperoxy fatty acid reductase
EC 1.11.1.23: (S)-2-hydroxypropylphosphonic acid epoxidase
EC 1.11.1.24: thioredoxin-dependent peroxiredoxin
EC 1.11.1.25: glutaredoxin-dependent peroxiredoxin
EC 1.11.1.26: NADH-dependent peroxiredoxin
EC 1.11.1.27: glutathione-dependent peroxiredoxin
EC 1.11.1.28: lipoyl-dependent peroxiredoxin
EC 1.11.1.29: mycoredoxin-dependent peroxiredoxin

EC 1.11.2 Peroxygenase

EC 1.12 Acting on hydrogen as donor

EC 1.12.1 With NAD⁺ or NADP⁺ as acceptor

EC 1.12.1.1: Now EC 1.12.7.2, ferredoxin hydrogenase
EC 1.12.1.2: hydrogen dehydrogenase
EC 1.12.1.3: hydrogen dehydrogenase (NADP⁺)
EC 1.12.1.4: hydrogenase (NAD⁺, ferredoxin)
EC 1.12.1.5: hydrogen dehydrogenase [NAD(P)⁺]

EC 1.12.2 With a cytochrome as acceptor

EC 1.12.2.1: cytochrome-c₃ hydrogenase

EC 1.12.5 With a quinone or similar compound as acceptor

EC 1.12.5.1: hydrogen:quinone oxidoreductase

EC 1.12.7 With an iron–sulfur protein as acceptor

EC 1.12.7.1: Now EC 1.12.7.2, ferredoxin hydrogenase
EC 1.12.7.2: ferredoxin hydrogenase

EC 1.12.98 With other known acceptors

EC 1.12.99 With unknown physiological acceptors

EC 1.12.99.1: Now EC 1.12.98.1, coenzyme F₄₂₀ hydrogenase
EC 1.12.99.2: Now shown to be two enzymes, EC 1.12.98.3, Methanosarcina-phenazine hydrogenase and EC 1.8.98.1, CoB—CoM heterodisulfide reductase
EC 1.12.99.3: Now EC 1.12.5.1, hydrogen:quinone oxidoreductase
EC 1.12.99.4: Now EC 1.12.98.2, 5,10-methenyltetrahydromethanopterin hydrogenase
EC 1.12.99.5: [[Identical to EC 1.13.11.47, 3-hydroxy-4-oxoquinoline 2,4-dioxygenase]]
EC 1.12.99.6: hydrogenase (acceptor)

EC 1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)

EC 1.13.11 With incorporation of two atoms of oxygen

EC 1.13.11.1: catechol 1,2-dioxygenase
EC 1.13.11.2: catechol 2,3-dioxygenase
EC 1.13.11.3: protocatechuate 3,4-dioxygenase
EC 1.13.11.4: gentisate 1,2-dioxygenase
EC 1.13.11.5: homogentisate 1,2-dioxygenase
EC 1.13.11.6: 3-hydroxyanthranilate 3,4-dioxygenase
EC 1.13.11.7: deleted
EC 1.13.11.8: protocatechuate 4,5-dioxygenase
EC 1.13.11.9: 2,5-dihydroxypyridine 5,6-dioxygenase
EC 1.13.11.10: 7,8-dihydroxykynurenate 8,8a-dioxygenase
EC 1.13.11.11: tryptophan 2,3-dioxygenase
EC 1.13.11.12: linoleate 13S-lipoxygenas
EC 1.13.11.13: The activity is the sum of several enzymatic and spontaneous reactions
EC 1.13.11.14: 2,3-dihydroxybenzoate 3,4-dioxygenase
EC 1.13.11.15: 3,4-dihydroxyphenylacetate 2,3-dioxygenase
EC 1.13.11.16: 3-carboxyethylcatechol 2,3-dioxygenase
EC 1.13.11.17: indole 2,3-dioxygenase
EC 1.13.11.18: persulfide dioxygenase
EC 1.13.11.19: cysteamine dioxygenase
EC 1.13.11.20: cysteine dioxygenase
EC 1.13.11.21: Now EC 1.14.99.36, β-carotene 15,15′-monooxygenase
EC 1.13.11.22: caffeate 3,4-dioxygenase
EC 1.13.11.23: 2,3-dihydroxyindole 2,3-dioxygenase
EC 1.13.11.24: quercetin 2,3-dioxygenase
EC 1.13.11.25: 3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione 4,5-dioxygenase
EC 1.13.11.26: peptide-tryptophan 2,3-dioxygenase
EC 1.13.11.27: 4-hydroxyphenylpyruvate dioxygenase
EC 1.13.11.28: 2,3-dihydroxybenzoate 2,3-dioxygenase
EC 1.13.11.29: stizolobate synthase
EC 1.13.11.30: stizolobinate synthase
EC 1.13.11.31: arachidonate 12-lipoxygenase
EC 1.13.11.32: Now EC 1.13.12.16, nitronate monooxygenase
EC 1.13.11.33: arachidonate 15-lipoxygenase
EC 1.13.11.34: arachidonate 5-lipoxygenase
EC 1.13.11.35: pyrogallol 1,2-oxygenase
EC 1.13.11.36: chloridazon-catechol dioxygenase
EC 1.13.11.37: hydroxyquinol 1,2-dioxygenase
EC 1.13.11.38: 1-hydroxy-2-naphthoate 1,2-dioxygenase
EC 1.13.11.39: biphenyl-2,3-diol 1,2-dioxygenase
EC 1.13.11.40: arachidonate 8-lipoxygenase
EC 1.13.11.41: 2,4′-dihydroxyacetophenone dioxygenase
EC 1.13.11.42: [[identical to EC 1.13.11.11, tryptophan 2,3-dioxygenase]]
EC 1.13.11.43: lignostilbene αβ-dioxygenase
EC 1.13.11.44: [[Activity is covered by EC 1.13.11.60, linoleate 8R-lipoxygenase and EC 5.4.4.6, 9,12-octadecadienoate 8-hydroperoxide 8S-isomerase|Activity is covered by EC 1.13.11.60, linoleate 8R-lipoxygenase and EC 5.4.4.6, 9,12-octadecadienoate 8-hydroperoxide 8S-isomerase]]
EC 1.13.11.45: linoleate 11-lipoxygenase
EC 1.13.11.46: 4-hydroxymandelate synthase
EC 1.13.11.47: 3-hydroxy-4-oxoquinoline 2,4-dioxygenase
EC 1.13.11.48: 3-hydroxy-2-methyl-quinolin-4-one 2,4-dioxygenase
EC 1.13.11.49: chlorite O₂-lyase
EC 1.13.11.50: acetylacetone-cleaving enzyme
EC 1.13.11.51: 9-cis-epoxycarotenoid dioxygenase
EC 1.13.11.52: indoleamine 2,3-dioxygenase
EC 1.13.11.53: acireductone dioxygenase (Ni²⁺-requiring)
EC 1.13.11.54: acireductone dioxygenase [iron(II)-requiring]
EC 1.13.11.55: sulfur oxygenase/reductase
EC 1.13.11.56: 1,2-dihydroxynaphthalene dioxygenase
EC 1.13.11.57: gallate dioxygenase
EC 1.13.11.58: linoleate 9S-lipoxygenase
EC 1.13.11.59: torulene dioxygenase
EC 1.13.11.60: inoleate 8R-lipoxygenase
EC 1.13.11.61: linolenate 9R-lipoxygenase
EC 1.13.11.62: linoleate 10R-lipoxygenase
EC 1.13.11.63: β-carotene 15,15′-dioxygenase
EC 1.13.11.64: 5-nitrosalicylate dioxygenase
EC 1.13.11.65: carotenoid isomerooxygenase
EC 1.13.11.66: hydroquinone 1,2-dioxygenase
EC 1.13.11.67: 8′-apo-β-carotenoid 14′,13′-cleaving dioxygenase
EC 1.13.11.68: 9-cis-β-carotene 9′,10′-cleaving dioxygenase
EC 1.13.11.69: carlactone synthase
EC 1.13.11.70: all-trans-10′-apo-β-carotenal 13,14-cleaving dioxygenase
EC 1.13.11.71: carotenoid-9′,10′-cleaving dioxygenase
EC 1.13.11.72: 2-hydroxyethylphosphonate dioxygenase
EC 1.13.11.73: methylphosphonate synthase
EC 1.13.11.74: 2-aminophenol 1,6-dioxygenase
EC 1.13.11.75: all-trans-8′-apo-β-carotenal 15,15′-oxygenase
EC 1.13.11.76: 2-amino-5-chlorophenol 1,6-dioxygenase
EC 1.13.11.77: oleate 10S-lipoxygenase
EC 1.13.11.78: 2-amino-1-hydroxyethylphosphonate dioxygenase (glycine-forming)
EC 1.13.11.79: aerobic 5,6-dimethylbenzimidazole synthase
EC 1.13.11.80: (3,5-dihydroxyphenyl)acetyl-CoA 1,2-dioxygenase
EC 1.13.11.81: 7,8-dihydroneopterin oxygenase
EC 1.13.11.82: 8′-apo-carotenoid 13,14-cleaving dioxygenase
EC 1.13.11.83: 4-hydroxy-3-prenylphenylpyruvate oxygenase
EC 1.13.11.84: crocetin dialdehyde synthase
EC 1.13.11.85: exo-cleaving rubber dioxygenase
EC 1.13.11.86: 5-aminosalicylate 1,2-dioxygenase
EC 1.13.11.87: endo-cleaving rubber dioxygenase
EC 1.13.11.88: isoeugenol monooxygenase
EC 1.13.11.89: (hydroxymethyl)phosphonate dioxygenase
EC 1.13.11.90: [1-hydroxy-2-(trimethylamino)ethyl]phosphonate dioxygenase (glycine-betaine-forming)
EC 1.13.11.91: 3-mercaptopropionate dioxygenase
EC 1.13.11.92: fatty acid α-dioxygenase

EC 1.13.12 With incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases)

EC 1.13.12.1: arginine 2-monooxygenase
EC 1.13.12.2: lysine 2-monooxygenase
EC 1.13.12.3: tryptophan 2-monooxygenase
EC 1.13.12.4: lactate 2-monooxygenase
EC 1.13.12.5: Renilla-type luciferase
EC 1.13.12.6: Cypridina-luciferin 2-monooxygenase
EC 1.13.12.7: firefly luciferase
EC 1.13.12.8: Watasenia-luciferin 2-monooxygenase
EC 1.13.12.9: phenylalanine 2-monooxygenase
EC 1.13.12.10: [[Reaction covered by EC 1.14.13.59, L-lysine 6-monooxygenase (NADPH)|Reaction covered by EC 1.14.13.59, L-lysine 6-monooxygenase (NADPH)]]
EC n1.13.12.11: [[The activity is due to EC 1.14.13.8, flavin-containing monooxygenase]]
EC 1.13.12.12: transferred to EC 1.13.11.67, 8-apo-β-carotenoid 14′,13′-cleaving dioxygenase
EC 1.13.12.13: Oplophorus-luciferin 2-monooxygenase
EC 1.13.12.14: Now EC 1.14.13.122, chlorophyllide-a oxygenase
EC 1.13.12.15: 3,4-dihydroxyphenylalanine oxidative deaminase
EC 1.13.12.16: nitronate monooxygenase
EC 1.13.12.17: dichloroarcyriaflavin A synthase
EC 1.13.12.18: dinoflagellate luciferase
EC 1.13.12.19: 2-oxoglutarate dioxygenase (ethene-forming)
EC 1.13.12.20: noranthrone monooxygenase
EC 1.13.12.21: tetracenomycin-F1 monooxygenase
EC 1.13.12.22: deoxynogalonate monooxygenase
EC 1.13.12.23: 4-hydroxy-3-prenylbenzoate synthase
EC 1.13.12.24: calcium-regulated photoprotein

EC 1.13.99 Miscellaneous

EC 1.13.99.1: inositol oxygenase
EC 1.13.99.2: Now EC 1.14.12.10, benzoate 1,2-dioxygenase
EC 1.13.99.3: tryptophan 2′-dioxygenase
EC 1.13.99.4: Now EC 1.14.12.9, 4-chlorophenylacetate 3,4-dioxygenase
EC 1.13.99.5: now EC 1.13.11.47, 3-hydroxy-4-oxoquinoline 2,4-dioxygenase

EC 1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen

[1]

[2]