유리딘 이인산 글루쿠론산

유리딘 이인산 글루쿠론산
이름
	우선명 (PIN) (2S,3S,4S,5R,6R)-6-[(3-{[(2R,3S,4R,5R)-5-(2,4-Dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}-1,3-dihydroxy-1,3-dioxo-1λ5,3λ5-diphosphoxan-1-yl)oxy]-3,4,5-trihydroxyoxane-2-carboxylic acid
식별자
CAS 번호	2616-64-0 ;
3D 모델 (JSmol)	Interactive image;
ChEBI	CHEBI:17200 ;
ChemSpider	19951236 ;
IUPHAR/BPS	1784;
MeSH	UDP+glucuronic+acid
PubChem CID	17473;
UNII	04SZC4MEFQ ;
CompTox Dashboard (EPA)	DTXSID00903961 ;
	InChI InChI=1S/C9H12N2O6.C6H12O13P2/c12-3-4-6(14)7(15)8(17-4)11-2-1-5(13)10-9(11)16;7-1-2(18-20(12,13)14)5(19-21(15,16)17)3(8)4(9)6(10)11/h1-2,4,6-8,12,14-15H,3H2,(H,10,13,16);1-5,8-9H,(H,10,11)(H2,12,13,14)(H2,15,16,17)/p-4/t4-,6-,7-,8-;2-,3+,4-,5+/m10/s1 Key: GIFKDHYZEJQSDD-BZYIUNRFSA-J ; InChI=1/C9H12N2O6.C6H12O13P2/c12-3-4-6(14)7(15)8(17-4)11-2-1-5(13)10-9(11)16;7-1-2(18-20(12,13)14)5(19-21(15,16)17)3(8)4(9)6(10)11/h1-2,4,6-8,12,14-15H,3H2,(H,10,13,16);1-5,8-9H,(H,10,11)(H2,12,13,14)(H2,15,16,17)/p-4/t4-,6-,7-,8-;2-,3+,4-,5+/m10/s1 Key: GIFKDHYZEJQSDD-DNQFPBLIBB;
	SMILES O[C@@H]1[C@@H](O)[C@H](O[C@@H]([C@H]1O)C(O)=O)O[P](O)(=O)O[P](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)[N]3C=C[C](=O)[NH][C]3=O;
성질
화학식	C15H22N2O18P2
몰 질량	580.285
	달리 명시된 경우를 제외하면, 표준상태(25 °C [77 °F], 100 kPa)에서 물질의 정보가 제공됨. 확인 (관련 정보 ?) 정보상자 각주

유리딘 이인산 글루쿠론산(영어: uridine diphosphate glucuronic acid) 또는 UDP-글루쿠론산(영어: UDP-glucuronic acid)은 다당류 생성에 사용되는 당뉴클레오타이드이며, 아스코르브산 생합성 과정의 중간생성물(영장류 및 기니피그는 제외)이다.

UDP-글루쿠론산은 NAD⁺를 보조 인자로 사용하는 UDP-포도당 6-탈수소효소(EC 1.1.1.22)에 의해 UDP-포도당으로부터 생성된다. UDP-글루쿠론산은 글루쿠로노실트랜스퍼레이스에 의해 촉매되는 반응에서 글루쿠로노실기의 공급원이다.^[1]^[2]

같이 보기

↑ Bontemps Y, Vuillermoz B, Antonicelli F, Perreau C, Danan JL, Maquart FX, Wegrowski Y (Jun 2003). “Specific protein-1 is a universal regulator of UDP-glucose dehydrogenase expression: its positive involvement in transforming growth factor-beta signaling and inhibition in hypoxia”. 《The Journal of Biological Chemistry》 278 (24): 21566–75. doi:10.1074/jbc.M209366200. PMID 12682078.
↑ Sommer BJ, Barycki JJ, Simpson MA (May 2004). “Characterization of human UDP-glucose dehydrogenase. CYS-276 is required for the second of two successive oxidations”. 《The Journal of Biological Chemistry》 279 (22): 23590–6. doi:10.1074/jbc.M401928200. PMID 15044486.

이름

우선명 (PIN) (2S,3S,4S,5R,6R)-6-[(3-{[(2R,3S,4R,5R)-5-(2,4-Dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}-1,3-dihydroxy-1,3-dioxo-1λ⁵,3λ⁵-diphosphoxan-1-yl)oxy]-3,4,5-trihydroxyoxane-2-carboxylic acid
식별자
CAS 번호	2616-64-0^예
3D 모델 (JSmol)	Interactive image
ChEBI	CHEBI:17200^아니오
ChemSpider	19951236^예
IUPHAR/BPS	1784
MeSH	UDP+glucuronic+acid
PubChem CID	17473
UNII	04SZC4MEFQ^예
CompTox Dashboard (EPA)	DTXSID00903961
InChI InChI=1S/C9H12N2O6.C6H12O13P2/c12-3-4-6(14)7(15)8(17-4)11-2-1-5(13)10-9(11)16;7-1-2(18-20(12,13)14)5(19-21(15,16)17)3(8)4(9)6(10)11/h1-2,4,6-8,12,14-15H,3H2,(H,10,13,16);1-5,8-9H,(H,10,11)(H2,12,13,14)(H2,15,16,17)/p-4/t4-,6-,7-,8-;2-,3+,4-,5+/m10/s1^예 Key: GIFKDHYZEJQSDD-BZYIUNRFSA-J^예 InChI=1/C9H12N2O6.C6H12O13P2/c12-3-4-6(14)7(15)8(17-4)11-2-1-5(13)10-9(11)16;7-1-2(18-20(12,13)14)5(19-21(15,16)17)3(8)4(9)6(10)11/h1-2,4,6-8,12,14-15H,3H2,(H,10,13,16);1-5,8-9H,(H,10,11)(H2,12,13,14)(H2,15,16,17)/p-4/t4-,6-,7-,8-;2-,3+,4-,5+/m10/s1 Key: GIFKDHYZEJQSDD-DNQFPBLIBB
SMILES O[C@@H]1[C@@H](O)[C@H](O[C@@H]([C@H]1O)C(O)=O)O[P](O)(=O)O[P](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)[N]3C=C[C](=O)[NH][C]3=O
성질
화학식	C₁₅H₂₂N₂O₁₈P₂
몰 질량	580.285
달리 명시된 경우를 제외하면, 표준상태(25 °C [77 °F], 100 kPa)에서 물질의 정보가 제공됨. 아니오 확인 (관련 정보 ^예아니오 ?) 정보상자 각주