Template:Cholesterol and steroid metabolism enzymes From Wikipedia the free encyclopedia vteMetabolism: lipid metabolism – ketones/cholesterol synthesis enzymes/steroid metabolismMevalonate pathwayTo HMG-CoA Acetyl-Coenzyme A acetyltransferase HMG-CoA synthase (regulated step) Ketogenesis HMG-CoA lyase 3-hydroxybutyrate dehydrogenase Thiophorase To Mevalonic acid HMG-CoA reductase To DMAPP Mevalonate kinase Phosphomevalonate kinase Pyrophosphomevalonate decarboxylase Isopentenyl-diphosphate delta isomerase Geranyl- Dimethylallyltranstransferase Geranyl pyrophosphate To cholesterolTo lanosterol Farnesyl-diphosphate farnesyltransferase Squalene monooxygenase Lanosterol synthase 7-Dehydrocholesterol path Lanosterol 14α-demethylase Sterol-C5-desaturase-like 7-Dehydrocholesterol reductase Desmosterol path 24-Dehydrocholesterol reductase To Bile acids Cholesterol 7α-hydroxylase Sterol 27-hydroxylase SteroidogenesisTo pregnenolone Cholesterol side-chain cleavage To corticosteroids aldosterone: 18-Hydroxylase cortisol/cortisone: 17α-Hydroxylase 11β-HSD 1 2 both: 3β-HSD 1 2 21-Hydroxylase 11β-Hydroxylase To sex hormonesTo androgens 17α-Hydroxylase 17,20-Lyase 3β-HSD 17β-HSD 5α-Reductase 1 2 To estrogens Aromatase 17β-HSD Other/ungrouped Steroid metabolism: sulfatase Steroid sulfatase sulfotransferase SULT1A1 SULT2A1 Steroidogenic acute regulatory protein Cholesterol total synthesis Reverse cholesterol transport
From Wikipedia the free encyclopedia From Wikipedia the free encyclopedia