Mnt IRES

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Mnt IRES
Predicted secondary structure and sequence conservation of IRES_mnt
Identifiers
SymbolIRES_mnt
RfamRF00457
Other data
RNA typeCis-reg; IRES
Domain(s)Eukaryota
GOGO:0043022
SOSO:0000243
PDB structuresPDBe

The Mnt internal ribosome entry site (IRES) is an RNA element. Mnt is a transcriptional repressor related to the Myc/Mad family of transcription factors. It is thought that this IRES allows efficient Mnt synthesis when cap-dependent translation initiation is reduced.[1]

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References[edit]

  1. ^ Stoneley M, Spencer JP, Wright SC (February 2001). "An internal ribosome entry segment in the 5' untranslated region of the mnt gene". Oncogene. 20 (7): 893–897. doi:10.1038/sj.onc.1204157. PMID 11314024.

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