Human parechovirus 1 (HPeV1) cis regulatory element (CRE)

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Human parechovirus 1 (HPeV1) cis regulatory element (CRE)
Predicted secondary structure and sequence conservation of Parecho_CRE
Identifiers
SymbolParecho_CRE
RfamRF00499
Other data
RNA typeCis-reg
Domain(s)Viruses
SOSO:0000233
PDB structuresPDBe

The Human Parechovirus 1 cis regulatory element is an RNA element which is located in the 5'-terminal 112 nucleotides of the genome of human parechovirus 1 (HPeV1). The element consists of two stem-loop structures (SL-A and SL-B) together with a pseudoknot. Disruption of any of these elements impairs both viral replication and growth.[1]

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References[edit]

  1. ^ Nateri AS, Hughes PJ, Stanway G (December 2002). "Terminal RNA replication elements in human parechovirus 1". Journal of Virology. 76 (24): 13116–13122. doi:10.1128/JVI.76.24.13116-13122.2002. PMC 136667. PMID 12438643.

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