Il Torneo di pallacanestro maschile NCAA Division I 2005 si concluse con la vittoria di North Carolina contro Illinois.
Sean May di North Carolina fu nominato Most Outstanding Player.
| Primo turno | | | Secondo turno | | | Semifinali regionali | | | Finali regionali | |
| | | | | | | | | | | | | | | | | | | |
| Illinois | 67 | | | | |
| Fairleigh Dickinson | 55 | | | 1 | Illinois | 71 | |
| Texas | 57 | | | 9 | Nevada | 59 | |
| Nevada | 61 | | | | | | 1 | Illinois | 77 | |
| Alabama | 73 | | | | | 12 | UW–Milwaukee | 63 | |
| UW–Milwaukee | 83 | | | 12 | UW–Milwaukee | 83 | | | | |
| Boston College | 85 | | | 4 | Boston College | 75 | |
| Pennsylvania | 65 | | | | 1 | Illinois | 90* | |
| LSU | 68 | | | | | | 3 | Arizona | 89 | |
| UAB | 82 | | | 11 | UAB | 63 | | | | |
| Arizona | 66 | | | 3 | Arizona | 85 | |
| Utah State | 53 | | | | | | 3 | Arizona | 79 | |
| Southern Illinois | 65 | | | | | 2 | Oklahoma State | 78 | |
| St. Mary's | 56 | | | 7 | Southern Illinois | 77 | | |
| Oklahoma State | 63 | | | 2 | Oklahoma State | 85 | |
| Southeastern Louisiana | 50 | | |
| Primo turno | | | Secondo turno | | | Semifinali regionali | | | Finali regionali | |
| | | | | | | | | | | | | | | | | | | |
| Washington | 88 | | | | |
| Montana | 77 | | | 1 | Washington | 97 | |
| Pacific | 79 | | | 8 | Pacific | 79 | |
| Pittsburgh | 71 | | | | | | 1 | Washington | 79 | |
| Georgia Tech | 80 | | | | | 4 | Louisville | 93 | |
| George Washington | 68 | | | 5 | Georgia Tech | 54 | | | | |
| Louisville | 68 | | | 4 | Louisville | 76 | |
| Louisiana-Lafayette | 62 | | | | 4 | Louisville | 93* | |
| Texas Tech | 78 | | | | | | 7 | West Virginia | 85 | |
| UCLA | 66 | | | 6 | Texas Tech | 71 | | | | |
| Gonzaga | 74 | | | 3 | Gonzaga | 69 | |
| Winthrop | 64 | | | | | | 6 | Texas Tech | 60 | |
| West Virginia | 63 | | | | | 7 | West Virginia | 65 | |
| Creighton | 61 | | | 7 | West Virginia | 111** | | |
| Wake Forest | 70 | | | 2 | Wake Forest | 105 | |
| UT-Chattanooga | 54 | | |
| 64 | Oakland | 79 | | Oakland ammessa al tabellone principale |
65 | Alabama A&M | 69 |
| Primo turno | | | Secondo turno | | | Semifinali regionali | | | Finali regionali | |
| | | | | | | | | | | | | | | | | | | |
| North Carolina | 96 | | | | |
| Oakland | 68 | | | 1 | North Carolina | 92 | |
| Minnesota | 53 | | | 9 | Iowa State | 65 | |
| Iowa State | 64 | | | | | | 1 | North Carolina | 67 | |
| Villanova | 55 | | | | | 5 | Villanova | 66 | |
| New Mexico | 47 | | | 5 | Villanova | 76 | | | | |
| Florida | 67 | | | 4 | Florida | 65 | |
| Ohio | 62 | | | | 1 | North Carolina | 88 | |
| Wisconsin | 57 | | | | | | 6 | Wisconsin | 82 | |
| Northern Iowa | 52 | | | 6 | Wisconsin | 71 | | | | |
| Kansas | 63 | | | 14 | Bucknell | 62 | |
| Bucknell | 64 | | | | | | 6 | Wisconsin | 65 | |
| Charlotte | 63 | | | | | 10 | North Carolina State | 56 | |
| North Carolina State | 75 | | | 10 | North Carolina State | 65 | | |
| Connecticut | 77 | | | 2 | Connecticut | 62 | |
| Central Florida | 71 | | |
| Primo turno | | | Secondo turno | | | Semifinali regionali | | | Finali regionali | |
| | | | | | | | | | | | | | | | | | | |
| Duke | 57 | | | | |
| Delaware State | 46 | | | 1 | Duke | 63 | |
| Stanford | 70 | | | 9 | Mississippi State | 55 | |
| Mississippi State | 93 | | | | | | 1 | Duke | 68 | |
| Michigan State | 89 | | | | | 5 | Michigan State | 78 | |
| Old Dominion | 81 | | | 5 | Michigan State | 72 | | | | |
| Syracuse | 57 | | | 13 | Vermont | 61 | |
| Vermont | 60* | | | | 5 | Michigan State | 94** | |
| Utah | 60 | | | | | | 2 | Kentucky | 88 | |
| UTEP | 54 | | | 6 | Utah | 67 | | | | |
| Oklahoma | 84 | | | 3 | Oklahoma | 58 | |
| Niagara | 67 | | | | | | 6 | Utah | 52 | |
| Cincinnati | 76 | | | | | 2 | Kentucky | 62 | |
| Iowa | 64 | | | 7 | Cincinnati | 60 | | |
| Kentucky | 72 | | | 2 | Kentucky | 69 | |
| Eastern Kentucky | 64 | | |
| Semifinali nazionali | | | Finale nazionale | |
| | | | | | | | | |
| CH1 | Illinois | 72 | | |
| AL4 | Louisville | 57 | | | CH1 | Illinois | 70 | |
| SY1 | North Carolina | 87 | | | SY1 | North Carolina | 75 | |
| AU5 | Michigan State | 71 | | | | |
- Naismith College Player of the Year: Andrew Bogut, Utah Utes
- John R. Wooden Award: Andrew Bogut, Utah Utes
- Oscar Robertson Trophy: Andrew Bogut, Utah Utes
- Adolph Rupp Trophy: J.J. Redick, Duke Blue Devils
- NABC Player of the Year: Andrew Bogut, Utah Utes
- AP Player of the Year: Andrew Bogut, Utah Utes
- Pete Newell Big Man Award: Andrew Bogut, Utah Utes
- NABC Defensive Player of the Year: Shelden Williams, Duke Blue Devils
- Frances Pomeroy Naismith Award: Nate Robinson, Washington Huskies
- Most Outstanding Player: Sean May, North Carolina Tar Heels
- NCAA All-Americans First Team:
- NCAA All-Americans Second Team:
- Naismith College Coach of the Year: Bruce Weber, Illinois Fighting Illini
- Henry Iba Award: Bruce Weber, Illinois Fighting Illini
- NABC Coach of the Year: Bruce Weber, Illinois Fighting Illini
- AP Coach of the Year: Tubby Smith, Kentucky Wildcats
- Chip Hilton Player of the Year Award: Ronald Ross, Texas Tech Red Raiders
- Clair Bee Coach of the Year Award: Tom Izzo, Michigan St. Spartans
- Legends of Coaching Award: Jim Calhoun, Connecticut Huskies