Post | Minister | Term | Party |
| President of South Africa | His Excellency Jacob Zuma | 2009 | 2018 | ANC |
| Deputy President of South Africa | His Excellency Cyril Ramaphosa | 2014 | 2018 | ANC |
| Minister in the Presidency | The Hon. Jeff Radebe MP | 2014 | 2018 | ANC |
| Minister of Women in the Presidency | The Hon. Susan Shabangu MP | 2014 | 2018 | ANC |
| Minister of Agriculture, Forestry and Fisheries | The Hon. Senzeni Zokwana MP | 2014 | 2019 | ANC |
| Minister of Arts and Culture | The Hon. Nathi Mthethwa MP | 2014 | 2019 | ANC |
| Minister of Basic Education | The Hon. Angie Motshekga MP | 2009 | – | ANC |
| Minister of Communications | The Hon. Mmamoloko Kubayi-Ngubane MP | 2017 | 2018 | ANC |
| The Hon. Ayanda Dlodlo MP | 2017 | 2017 | ANC |
| The Hon. Faith Muthambi MP | 2014 | 2017 | ANC |
| Minister of Cooperative Governance and Traditional Affairs | The Hon. David van Rooyen MP | 2015 | 2018 | ANC |
| The Hon. Pravin Gordhan MP | 2014 | 2015 | ANC |
| Minister of Defence and Military Veterans | The Hon. Nosiviwe Mapisa-Nqakula MP | 2013 | 2021 | ANC |
| Minister of Economic Development | The Hon. Ebrahim Patel MP | 2009 | 2019 | ANC |
| Minister of Energy | The Hon. David Mahlobo MP | 2017 | 2018 | ANC |
| The Hon. Tina Joemat-Pettersson MP | 2014 | 2017 | ANC |
| Minister of Environmental Affairs | The Hon. Edna Molewa MP | 2014 | 2018 | ANC |
| Minister of Finance | The Hon. Malusi Gigaba MP | 2017 | 2018 | ANC |
| The Hon. Pravin Gordhan MP | 2015 | 2017 | ANC |
| The Hon. David van Rooyen MP | 2015 | 2015 | ANC |
| The Hon. Nhlanhla Nene MP | 2014 | 2015 | ANC |
| Minister of Health | The Hon. Aaron Motsoaledi MP | 2009 | 2019 | ANC |
| Minister of Higher Education and Training | The Hon. Hlengiwe Mkhize MP | 2017 | 2018 | ANC |
| The Hon. Blade Nzimande MP | 2009 | 2017 | ANC |
| Minister of Home Affairs | The Hon. Malusi Gigaba MP | 2014 | 2019 | ANC |
| Minister of Human Settlements | The Hon. Lindiwe Sisulu MP | 2014 | 2018 | ANC |
| Minister of International Relations and Cooperation | The Hon. Maite Nkoana-Mashabane MP | 2009 | 2018 | ANC |
| Minister of Justice and Correctional Services | The Hon. Michael Masutha MP | 2014 | 2019 | ANC |
| Minister of Labour | The Hon. Mildred Oliphant MP | 2010 | 2019 | ANC |
| Minister of Mineral Resources | The Hon. Mosebenzi Zwane MP | 2015 | 2018 | ANC |
| The Hon. Ngoako Ramatlhodi MP | 2014 | 2015 | ANC |
| Minister of Police | The Hon. Fikile Mbalula MP | 2017 | 2018 | ANC |
| The Hon. Nkosinathi Nhleko MP | 2014 | 2017 | ANC |
| Minister of Public Enterprises | The Hon. Lynne Brown MP | 2014 | 2018 | ANC |
| Minister of Public Service and Administration | The Hon. Faith Muthambi MP | 2017[2] | 2018 | ANC |
| The Hon. Ngoako Ramatlhodi MP | 2015 | 2017 | ANC |
| The Hon. Collins Chabane MP | 2014 | 2015 | ANC |
| Minister of Public Works | The Hon. Nathi Nhleko MP | 2017 | 2018 | ANC |
| The Hon. Thulas Nxesi MP | 2011 | 2017 | ANC |
| Minister of Rural Development and Land Reform | The Hon. Gugile Nkwinti MP | 2009 | 2018 | ANC |
| Minister of Science and Technology | The Hon. Naledi Pandor MP | 2014 | 2018 | ANC |
| Minister of Small Business Development | The Hon. Lindiwe Zulu MP | 2014 | 2019 | ANC |
| Minister of Social Development | The Hon. Bathabile Dlamini MP | 2010 | 2018 | ANC |
| Minister of Sport and Recreation | The Hon. Thembelani Nxesi MP | 2017 | 2018 | ANC |
| The Hon. Fikile Mbalula MP | 2010 | 2017 | ANC |
| Minister of State Security | The Hon. Bongani Bongo MP | 2017 | 2018 | ANC |
| The Hon. David Mahlobo MP | 2014 | 2017 | ANC |
| Minister of Telecommunications and Postal Services | The Hon. Siyabonga Cwele MP | 2014 | 2018 | ANC |
| Minister of Tourism | The Hon. Tokozile Xasa MP | 2017 | 2018 | ANC |
| The Hon. Derek Hanekom MP | 2014 | 2017 | ANC |
| Minister of Trade and Industry | The Hon. Rob Davies MP | 2009 | 2019 | ANC |
| Minister of Transport | The Hon. Joe Maswanganyi MP | 2017 | 2018 | ANC |
| The Hon. Dipuo Peters MP | 2013 | 2017 | ANC |
| Minister of Water and Sanitation | The Hon. Nomvula Mokonyane MP | 2014 | 2018 | ANC |